Gene: ENSMUSG00000029454 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000029454
Transcript Identifier
ENSMUST00000031410
Gene Type
Coding gene
Location
5 : 121525145-121545200 : negative

Family Information

Homologous gene family
HOM03P000001
(4368 genes in 39 species)
specific family
Orthologous gene family
ORTHO03P031778
(3 genes in 2 species)
specific family
Duplication type
Tandem duplicate   and   Block duplicate

Descriptions

gene_descr
MAP kinase-activated protein kinase 5

Identifiers

Type Value
UniprotO54992
MGI1333110

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000165
IBA
Genome ProjectMAPK cascade
GO:0006417
ISS, ISO
Genome Projectregulation of translation
GO:0006468
IEA
Genome Projectprotein phosphorylation
GO:0007166
IBA
Genome Projectcell surface receptor signaling pathway
GO:0007265
IMP
ISO
Genome ProjectRas protein signal transduction
GO:0016310
IEA
Genome Projectphosphorylation
GO:0018105
IBA
Genome Projectpeptidyl-serine phosphorylation
GO:0032007
IDA
Genome Projectnegative regulation of TOR signaling
GO:0046777
ISS, ISO, IBA
Genome Projectprotein autophosphorylation
GO:0090400
IMP
ISO
Genome Projectstress-induced premature senescence

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000166
IEA
Genome Projectnucleotide binding
GO:0002039
IDA
ISO
Genome Projectp53 binding
GO:0004672
IDA
IEA
Genome Projectprotein kinase activity
GO:0004674
IDA
ISO
IEA
Genome Projectprotein serine/threonine kinase activity
GO:0004683
IBA
Genome Projectcalmodulin-dependent protein kinase activity
GO:0004871
IBA
Genome Projectsignal transducer activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0005516
IBA
Genome Projectcalmodulin binding
GO:0005524
IEA
Genome ProjectATP binding
GO:0009931
IBA
Genome Projectcalcium-dependent protein serine/threonine kinase activity
GO:0016301
IEA
Genome Projectkinase activity
GO:0016740
IEA
Genome Projecttransferase activity
GO:0051019
IPI
Genome Projectmitogen-activated protein kinase binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IDA
IEA
Genome Projectnucleus
GO:0005654
ISO
Genome Projectnucleoplasm
GO:0005737
IDA
ISO
IEA
Genome Projectcytoplasm

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000719Protein kinase domain
IPR002290Serine/threonine/dual specificity protein kinase, catalytic domain
IPR008271Serine/threonine-protein kinase, active site
IPR011009Protein kinase-like domain
IPR027442MAP kinase activated protein kinase, C-terminal domain

No MapMan annotations defined for this gene.