Gene: ENSMUSG00000029378 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000029378
Transcript Identifier
ENSMUST00000031325
Gene Type
Coding gene
Location
5 : 91139814-91146731 : positive

Family Information

Homologous gene family
HOM03P038240
(2 genes in 2 species)
specific family

Descriptions

gene_descr
amphiregulin

Identifiers

Type Value
UniprotP31955
UniprotQ4FJT2
MGI88068

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0007173
ISO, IBA
IEA
Genome Projectepidermal growth factor receptor signaling pathway
GO:0007186
ISO
IEA
Genome ProjectG-protein coupled receptor signaling pathway
GO:0008284
IBA
IEA
Genome Projectpositive regulation of cell proliferation
GO:0014009
IEA
Genome Projectglial cell proliferation
GO:0014070
IEA
Genome Projectresponse to organic cyclic compound
GO:0031175
IEA
Genome Projectneuron projection development
GO:0032355
IDA
Genome Projectresponse to estradiol
GO:0042327
IEA
Genome Projectpositive regulation of phosphorylation
GO:0042542
IEA
Genome Projectresponse to hydrogen peroxide
GO:0043434
IEA
Genome Projectresponse to peptide hormone
GO:0045668
IEA
Genome Projectnegative regulation of osteoblast differentiation
GO:0045740
ISO
IEA
Genome Projectpositive regulation of DNA replication
GO:0051384
IEA
Genome Projectresponse to glucocorticoid
GO:0051591
IEA
Genome Projectresponse to cAMP
GO:0060598
IMP
Genome Projectdichotomous subdivision of terminal units involved in mammary gland duct morphogenesis
GO:0060744
IMP
Genome Projectmammary gland branching involved in thelarche
GO:0060749
IGI
Genome Projectmammary gland alveolus development
GO:0060750
IMP
Genome Projectepithelial cell proliferation involved in mammary gland duct elongation

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005125
IEA
Genome Projectcytokine activity
GO:0005154
IBA
IEA
Genome Projectepidermal growth factor receptor binding
GO:0008083
IBA
IEA
Genome Projectgrowth factor activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005615
ISO, IBA
IEA
Genome Projectextracellular space
GO:0005622
IDA
Genome Projectintracellular
GO:0005634
IDA
Genome Projectnucleus
GO:0005737
IDA
Genome Projectcytoplasm
GO:0009986
ISO
IEA
Genome Projectcell surface
GO:0016020
IEA
Genome Projectmembrane
GO:0016021
IEA
Genome Projectintegral component of membrane

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000742EGF-like domain
IPR013032EGF-like, conserved site
IPR015497Epidermal growth factor receptor ligand

No MapMan annotations defined for this gene.