Gene: ENSMUSG00000029053 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000029053
Transcript Identifier
ENSMUST00000030922
Gene Type
Coding gene
Location
4 : 155262444-155361222 : negative

Family Information

Homologous gene family
HOM03P000015
(1237 genes in 39 species)
specific family
Orthologous gene family
ORTHO03P014902
(6 genes in 4 species)
specific family

Descriptions

gene_descr
protein kinase C, zeta

Identifiers

Type Value
UniprotQ02956
MGI97602

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000226
IMP, IGI
Genome Projectmicrotubule cytoskeleton organization
GO:0001954
IEA
Genome Projectpositive regulation of cell-matrix adhesion
GO:0006468
IDA
ISO
IEA
Genome Projectprotein phosphorylation
GO:0006954
IEA
Genome Projectinflammatory response
GO:0007165
IEA
Genome Projectsignal transduction
GO:0007166
IEA
Genome Projectcell surface receptor signaling pathway
GO:0007616
IEA
Genome Projectlong-term memory
GO:0008284
IEA
Genome Projectpositive regulation of cell proliferation
GO:0008286
IEA
Genome Projectinsulin receptor signaling pathway
GO:0016310
IEA
Genome Projectphosphorylation
GO:0016477
IEA
Genome Projectcell migration
GO:0018105
ISO
IEA
Genome Projectpeptidyl-serine phosphorylation
GO:0030010
ISS
IEA
Genome Projectestablishment of cell polarity
GO:0031333
ISO
IEA
Genome Projectnegative regulation of protein complex assembly
GO:0031532
IEA
Genome Projectactin cytoskeleton reorganization
GO:0031584
IEA
Genome Projectactivation of phospholipase D activity
GO:0032148
IEA
Genome Projectactivation of protein kinase B activity
GO:0032753
IMP
Genome Projectpositive regulation of interleukin-4 production
GO:0032869
IEA
Genome Projectcellular response to insulin stimulus
GO:0034613
IEA
Genome Projectcellular protein localization
GO:0035556
IEA
Genome Projectintracellular signal transduction
GO:0043066
IEA
Genome Projectnegative regulation of apoptotic process
GO:0045630
IMP
Genome Projectpositive regulation of T-helper 2 cell differentiation
GO:0046326
IEA
Genome Projectpositive regulation of glucose import
GO:0046627
ISO
IEA
Genome Projectnegative regulation of insulin receptor signaling pathway
GO:0046628
ISS
IEA
Genome Projectpositive regulation of insulin receptor signaling pathway
GO:0047496
IEA
Genome Projectvesicle transport along microtubule
GO:0050732
ISO
IEA
Genome Projectnegative regulation of peptidyl-tyrosine phosphorylation
GO:0050806
IEA
Genome Projectpositive regulation of synaptic transmission
GO:0051092
ISS
IEA
Genome Projectpositive regulation of NF-kappaB transcription factor activity
GO:0051222
IEA
Genome Projectpositive regulation of protein transport
GO:0051291
IEA
Genome Projectprotein heterooligomerization
GO:0051346
IEA
Genome Projectnegative regulation of hydrolase activity
GO:0051899
IEA
Genome Projectmembrane depolarization
GO:0060081
IEA
Genome Projectmembrane hyperpolarization
GO:0060291
ISS
IEA
Genome Projectlong-term synaptic potentiation
GO:0070374
ISS, ISO
IEA
Genome Projectpositive regulation of ERK1 and ERK2 cascade
GO:0070528
IEA
Genome Projectprotein kinase C signaling
GO:0072659
IMP
Genome Projectprotein localization to plasma membrane
GO:1990138
IGI
Genome Projectneuron projection extension
GO:2000463
ISS
IEA
Genome Projectpositive regulation of excitatory postsynaptic potential
GO:2000553
IMP
Genome Projectpositive regulation of T-helper 2 cell cytokine production
GO:2000664
IMP
Genome Projectpositive regulation of interleukin-5 secretion
GO:2000667
IMP
Genome Projectpositive regulation of interleukin-13 secretion
GO:2001181
IMP
Genome Projectpositive regulation of interleukin-10 secretion

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000166
IEA
Genome Projectnucleotide binding
GO:0004672
IDA
ISO
IEA
Genome Projectprotein kinase activity
GO:0004674
IDA
ISO
IEA
Genome Projectprotein serine/threonine kinase activity
GO:0004697
IEA
Genome Projectprotein kinase C activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0005524
IEA
Genome ProjectATP binding
GO:0015459
IEA
Genome Projectpotassium channel regulator activity
GO:0016301
IEA
Genome Projectkinase activity
GO:0016740
IEA
Genome Projecttransferase activity
GO:0019901
IEA
Genome Projectprotein kinase binding
GO:0019904
IEA
Genome Projectprotein domain specific binding
GO:0043274
IEA
Genome Projectphospholipase binding
GO:0046872
IEA
Genome Projectmetal ion binding
GO:0071889
IEA
Genome Project14-3-3 protein binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IDA
Genome Projectnucleus
GO:0005635
IDA
Genome Projectnuclear envelope
GO:0005737
IDA
IEA
Genome Projectcytoplasm
GO:0005768
IEA
Genome Projectendosome
GO:0005815
IGI
Genome Projectmicrotubule organizing center
GO:0005829
IEA
Genome Projectcytosol
GO:0005886
IDA
IEA
Genome Projectplasma membrane
GO:0005911
ISS, ISO
IEA
Genome Projectcell-cell junction
GO:0005923
IDA
Genome Projectbicellular tight junction
GO:0005938
IDA
Genome Projectcell cortex
GO:0016324
IDA
Genome Projectapical plasma membrane
GO:0016363
IDA
Genome Projectnuclear matrix
GO:0030054
IEA
Genome Projectcell junction
GO:0031252
IEA
Genome Projectcell leading edge
GO:0031941
IEA
Genome Projectfilamentous actin
GO:0035748
IDA
Genome Projectmyelin sheath abaxonal region
GO:0043203
IDA
Genome Projectaxon hillock
GO:0043231
IEA
Genome Projectintracellular membrane-bounded organelle
GO:0043234
IDA
IEA
Genome Projectprotein complex
GO:0045121
IEA
Genome Projectmembrane raft
GO:0045179
IDA
Genome Projectapical cortex
GO:0048471
IEA
Genome Projectperinuclear region of cytoplasm
GO:0070062
ISO
IEA
Genome Projectextracellular exosome

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000270PB1 domain
IPR000719Protein kinase domain
IPR000961AGC-kinase, C-terminal
IPR002219Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
IPR002290Serine/threonine/dual specificity protein kinase, catalytic domain
IPR008271Serine/threonine-protein kinase, active site
IPR011009Protein kinase-like domain
IPR012233Protein kinase C
IPR017441Protein kinase, ATP binding site
IPR020454Diacylglycerol/phorbol-ester binding

No MapMan annotations defined for this gene.