Gene: ENSMUSG00000029050 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000029050
Transcript Identifier
ENSMUST00000030917
Gene Type
Coding gene
Location
4 : 155157341-155222520 : negative

Family Information

Homologous gene family
HOM03P010259
(8 genes in 3 species)
specific family
Orthologous gene family
ORTHO03P071191
(2 genes in 2 species)
specific family

Descriptions

gene_descr
ski sarcoma viral oncogene homolog (avian)

Identifiers

Type Value
UniprotB1AUF1
MGI98310

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000122
IGI
ISO
IEA
Genome Projectnegative regulation of transcription from RNA polymerase II promoter
GO:0001843
IMP
Genome Projectneural tube closure
GO:0002089
IMP
Genome Projectlens morphogenesis in camera-type eye
GO:0006351
IEA
Genome Projecttranscription, DNA-templated
GO:0008285
ISO
IEA
Genome Projectnegative regulation of cell proliferation
GO:0009948
IMP
Genome Projectanterior/posterior axis specification
GO:0010626
ISO
IEA
Genome Projectnegative regulation of Schwann cell proliferation
GO:0014902
IDA, IGI
ISO
IEA
Genome Projectmyotube differentiation
GO:0021772
IMP
Genome Projectolfactory bulb development
GO:0022011
IMP
Genome Projectmyelination in peripheral nervous system
GO:0030326
IMP
Genome Projectembryonic limb morphogenesis
GO:0030512
IGI
ISO
IEA
Genome Projectnegative regulation of transforming growth factor beta receptor signaling pathway
GO:0030514
IGI
ISO
IEA
Genome Projectnegative regulation of BMP signaling pathway
GO:0031064
IGI
Genome Projectnegative regulation of histone deacetylation
GO:0032926
ISO
IEA
Genome Projectnegative regulation of activin receptor signaling pathway
GO:0035019
IDA
Genome Projectsomatic stem cell population maintenance
GO:0042981
IBA
Genome Projectregulation of apoptotic process
GO:0043010
IMP
Genome Projectcamera-type eye development
GO:0043388
ISO
IEA
Genome Projectpositive regulation of DNA binding
GO:0043585
IMP
Genome Projectnose morphogenesis
GO:0045668
ISO
IEA
Genome Projectnegative regulation of osteoblast differentiation
GO:0045944
IDA, IGI
Genome Projectpositive regulation of transcription from RNA polymerase II promoter
GO:0048147
IMP
Genome Projectnegative regulation of fibroblast proliferation
GO:0048593
IMP
Genome Projectcamera-type eye morphogenesis
GO:0048741
IMP
Genome Projectskeletal muscle fiber development
GO:0060021
IMP
Genome Projectpalate development
GO:0060041
IMP
Genome Projectretina development in camera-type eye
GO:0060325
IMP
Genome Projectface morphogenesis
GO:0060349
IMP
Genome Projectbone morphogenesis
GO:0060395
ISO
IEA
Genome ProjectSMAD protein signal transduction
GO:0070207
ISO
IEA
Genome Projectprotein homotrimerization

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0003682
IGI
Genome Projectchromatin binding
GO:0003714
ISO
IEA
Genome Projecttranscription corepressor activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0008270
ISO
IEA
Genome Projectzinc ion binding
GO:0019901
ISO
IEA
Genome Projectprotein kinase binding
GO:0019904
ISO
IEA
Genome Projectprotein domain specific binding
GO:0031625
ISO
IEA
Genome Projectubiquitin protein ligase binding
GO:0046332
ISO, IBA
IEA
Genome ProjectSMAD binding
GO:0046811
IGI
Genome Projecthistone deacetylase inhibitor activity
GO:0070491
ISO
IEA
Genome Projectrepressing transcription factor binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IDA
ISO
IEA
Genome Projectnucleus
GO:0005667
IPI
Genome Projecttranscription factor complex
GO:0005737
IDA
Genome Projectcytoplasm
GO:0005813
ISO
IEA
Genome Projectcentrosome
GO:0016604
ISO
IEA
Genome Projectnuclear body
GO:0016605
ISO
IEA
Genome ProjectPML body
GO:0017053
IDA
Genome Projecttranscriptional repressor complex
GO:0043234
ISO
IEA
Genome Projectprotein complex

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR003380Transforming protein Ski
IPR009061Putative DNA-binding domain
IPR010919SAND domain-like
IPR014890c-SKI SMAD4-binding domain
IPR023216Transcription regulator SKI/SnoN
IPR028760Ski oncogene

No MapMan annotations defined for this gene.