Gene: ENSMUSG00000029009 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000029009
Transcript Identifier
ENSMUST00000069604
Gene Type
Coding gene
Location
4 : 148041212-148055588 : positive

Family Information

Homologous gene family
HOM03P001824
(44 genes in 31 species)
specific family
Orthologous gene family
ORTHO03P001013
(41 genes in 31 species)
specific family

Descriptions

gene_descr
5,10-methylenetetrahydrofolate reductase

Identifiers

Type Value
UniprotA2A7F7
MGI106639

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001666
IEA
Genome Projectresponse to hypoxia
GO:0006555
ISO
IEA
Genome Projectmethionine metabolic process
GO:0006730
IBA
Genome Projectone-carbon metabolic process
GO:0009086
IMP
Genome Projectmethionine biosynthetic process
GO:0031060
ISO
IEA
Genome Projectregulation of histone methylation
GO:0033274
IEA
Genome Projectresponse to vitamin B2
GO:0035999
ISO
IEA
Genome Projecttetrahydrofolate interconversion
GO:0042493
IEA
Genome Projectresponse to drug
GO:0043200
IEA
Genome Projectresponse to amino acid
GO:0046500
IEA
Genome ProjectS-adenosylmethionine metabolic process
GO:0046653
IEA
Genome Projecttetrahydrofolate metabolic process
GO:0050667
ISO
IEA
Genome Projecthomocysteine metabolic process
GO:0051593
IEA
Genome Projectresponse to folic acid
GO:0055114
IEA
Genome Projectoxidation-reduction process
GO:0070555
IEA
Genome Projectresponse to interleukin-1
GO:0070829
ISO
IEA
Genome Projectheterochromatin maintenance

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004489
IMP
ISO
IEA
Genome Projectmethylenetetrahydrofolate reductase (NAD(P)H) activity
GO:0016491
IEA
Genome Projectoxidoreductase activity
GO:0032403
ISO
IEA
Genome Projectprotein complex binding
GO:0050660
ISO
IEA
Genome Projectflavin adenine dinucleotide binding
GO:0050661
IEA
Genome ProjectNADP binding
GO:0072341
ISO
IEA
Genome Projectmodified amino acid binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005829
IBA
IEA
Genome Projectcytosol
GO:0043005
IEA
Genome Projectneuron projection

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR003171Methylenetetrahydrofolate reductase
IPR004621Eukaryotic-type methylenetetrahydrofolate reductase
IPR029041FAD-linked oxidoreductase-like

No MapMan annotations defined for this gene.