Gene: ENSMUSG00000028914 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000028914
Transcript Identifier
ENSMUST00000030747
Gene Type
Coding gene
Location
4 : 141793855-141813687 : positive

Family Information

Homologous gene family
HOM03P003300
(30 genes in 4 species)
specific family

Descriptions

gene_descr
caspase 9

Identifiers

Type Value
UniprotQ8C3Q9
MGI1277950

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006508
RCA
IEA
Genome Projectproteolysis
GO:0006915
IDA, IMP
IEA
Genome Projectapoptotic process
GO:0006919
IMP
Genome Projectactivation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0006974
IMP
ISO
IEA
Genome Projectcellular response to DNA damage stimulus
GO:0007568
IEA
Genome Projectaging
GO:0008630
ISS, ISO, IBA
IEA
Genome Projectintrinsic apoptotic signaling pathway in response to DNA damage
GO:0009411
IMP
Genome Projectresponse to UV
GO:0014070
IEA
Genome Projectresponse to organic cyclic compound
GO:0032025
IEA
Genome Projectresponse to cobalt ion
GO:0032355
IEA
Genome Projectresponse to estradiol
GO:0032496
IEA
Genome Projectresponse to lipopolysaccharide
GO:0034349
IEA
Genome Projectglial cell apoptotic process
GO:0034644
ISS, ISO
IEA
Genome Projectcellular response to UV
GO:0042770
ISS, ISO
IEA
Genome Projectsignal transduction in response to DNA damage
GO:0042981
IEA
Genome Projectregulation of apoptotic process
GO:0043065
IEA
Genome Projectpositive regulation of apoptotic process
GO:0043525
IMP, IGI
Genome Projectpositive regulation of neuron apoptotic process
GO:0046677
IEA
Genome Projectresponse to antibiotic
GO:0070059
NAS
Genome Projectintrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
GO:0071407
IEA
Genome Projectcellular response to organic cyclic compound
GO:0071549
IDA
Genome Projectcellular response to dexamethasone stimulus
GO:2001020
ISS, ISO
IEA
Genome Projectregulation of response to DNA damage stimulus

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004197
IDA
IEA
Genome Projectcysteine-type endopeptidase activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0008233
IDA
ISO, RCA
IEA
Genome Projectpeptidase activity
GO:0008234
IEA
Genome Projectcysteine-type peptidase activity
GO:0016787
IEA
Genome Projecthydrolase activity
GO:0017124
ISS, ISO
IEA
Genome ProjectSH3 domain binding
GO:0019901
ISS, ISO
IEA
Genome Projectprotein kinase binding
GO:0097199
IBA
Genome Projectcysteine-type endopeptidase activity involved in apoptotic signaling pathway

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IDA
IEA
Genome Projectnucleus
GO:0005737
IBA
IEA
Genome Projectcytoplasm
GO:0005739
IEA
Genome Projectmitochondrion
GO:0005829
IDA
ISO
IEA
Genome Projectcytosol
GO:0043293
ISO
IEA
Genome Projectapoptosome

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR001309Peptidase C14, ICE, catalytic subunit p20
IPR001315CARD domain
IPR002138Peptidase C14, caspase non-catalytic subunit p10
IPR011029Death-like domain
IPR011600Peptidase C14, caspase domain
IPR015917Peptidase C14A, caspase precursor p45, core
IPR016129Peptidase C14, ICE, catalytic subunit p20, active site
IPR017350Peptidase C14A, Casp1-type
IPR029030Caspase-like domain

No MapMan annotations defined for this gene.