Gene: ENSMUSG00000028680 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000028680
Transcript Identifier
ENSMUST00000076859
Gene Type
Coding gene
Location
4 : 117128987-117133864 : negative

Family Information

Homologous gene family
HOM03P000001
(4368 genes in 39 species)
specific family
Duplication type
Tandem duplicate   and   Block duplicate

Descriptions

gene_descr
polo-like kinase 3

Identifiers

Type Value
UniprotQ6P571
MGI109604

Toolbox

Explore

Create

View

Browse

 

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000082
ISO
IEA
Genome ProjectG1/S transition of mitotic cell cycle
GO:0000122
ISO
IEA
Genome Projectnegative regulation of transcription from RNA polymerase II promoter
GO:0000302
ISO
IEA
Genome Projectresponse to reactive oxygen species
GO:0006468
IEA
Genome Projectprotein phosphorylation
GO:0006970
ISO
IEA
Genome Projectresponse to osmotic stress
GO:0006974
ISO
IEA
Genome Projectcellular response to DNA damage stimulus
GO:0009314
ISO
IEA
Genome Projectresponse to radiation
GO:0016310
IEA
Genome Projectphosphorylation
GO:0031122
ISO
IEA
Genome Projectcytoplasmic microtubule organization
GO:0032465
ISO
IEA
Genome Projectregulation of cytokinesis
GO:0043066
ISO
IEA
Genome Projectnegative regulation of apoptotic process
GO:0051302
ISO
IEA
Genome Projectregulation of cell division
GO:0090166
ISO
IEA
Genome ProjectGolgi disassembly
GO:0090316
ISO
IEA
Genome Projectpositive regulation of intracellular protein transport
GO:2000777
ISO
IEA
Genome Projectpositive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000166
IEA
Genome Projectnucleotide binding
GO:0002039
ISO
IEA
Genome Projectp53 binding
GO:0004672
IEA
Genome Projectprotein kinase activity
GO:0004674
ISO
IEA
Genome Projectprotein serine/threonine kinase activity
GO:0005524
IEA
Genome ProjectATP binding
GO:0016301
IEA
Genome Projectkinase activity
GO:0016740
IEA
Genome Projecttransferase activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000785
IDA
Genome Projectchromatin
GO:0005634
ISO
IEA
Genome Projectnucleus
GO:0005730
ISO
IEA
Genome Projectnucleolus
GO:0005737
ISO
IEA
Genome Projectcytoplasm
GO:0005795
ISO
IEA
Genome ProjectGolgi stack
GO:0005813
ISO
IEA
Genome Projectcentrosome
GO:0030425
IEA
Genome Projectdendrite
GO:0043025
IEA
Genome Projectneuronal cell body

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000719Protein kinase domain
IPR000959POLO box duplicated domain
IPR002290Serine/threonine/dual specificity protein kinase, catalytic domain
IPR008271Serine/threonine-protein kinase, active site
IPR011009Protein kinase-like domain
IPR017441Protein kinase, ATP binding site
IPR020658Serine/threonine-protein kinase Plk3

No MapMan annotations defined for this gene.