Gene: ENSMUSG00000028405 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000028405
Transcript Identifier
ENSMUST00000102973
Gene Type
Coding gene
Location
4 : 40163749-40197667 : positive

Family Information

Homologous gene family
HOM03P003729
(26 genes in 10 species)
specific family

Descriptions

gene_descr
aconitase 1

Identifiers

Type Value
UniprotP28271
MGI87879

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006099
IEA
Genome Projecttricarboxylic acid cycle
GO:0006101
ISS, ISO
IEA
Genome Projectcitrate metabolic process
GO:0006417
IMP
Genome Projectregulation of translation
GO:0006879
IMP, IGI
IEA
Genome Projectcellular iron ion homeostasis
GO:0008152
IEA
Genome Projectmetabolic process
GO:0009791
IGI
Genome Projectpost-embryonic development
GO:0010040
ISS, ISO
IEA
Genome Projectresponse to iron(II) ion
GO:0010468
IGI
Genome Projectregulation of gene expression
GO:0050892
IGI
Genome Projectintestinal absorption

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0003723
ISO
IEA
Genome ProjectRNA binding
GO:0003994
IDA
ISS, ISO
IEA
Genome Projectaconitate hydratase activity
GO:0016829
IEA
Genome Projectlyase activity
GO:0030350
IDA
ISS, ISO
IEA
Genome Projectiron-responsive element binding
GO:0046872
IEA
Genome Projectmetal ion binding
GO:0051536
IEA
Genome Projectiron-sulfur cluster binding
GO:0051539
ISS, ISO
IEA
Genome Project4 iron, 4 sulfur cluster binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005737
IDA
ISO
IEA
Genome Projectcytoplasm
GO:0005739
IDA
ISO
IEA
Genome Projectmitochondrion
GO:0005783
ISO
IEA
Genome Projectendoplasmic reticulum
GO:0005794
ISO
IEA
Genome ProjectGolgi apparatus
GO:0005829
IDA
ISO
IEA
Genome Projectcytosol
GO:0070062
ISO
IEA
Genome Projectextracellular exosome

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000573Aconitase A/isopropylmalate dehydratase small subunit, swivel domain
IPR001030Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain
IPR006249Aconitase/Iron-responsive element-binding protein 2
IPR015928Aconitase/3-isopropylmalate dehydratase, swivel
IPR015931Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3
IPR015932Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2
IPR015937Aconitase/isopropylmalate dehydratase
IPR018136Aconitase family, 4Fe-4S cluster binding site
IPR029784Iron regulatory protein 1

No MapMan annotations defined for this gene.