Gene: ENSMUSG00000028289 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000028289
Transcript Identifier
ENSMUST00000029964
Gene Type
Coding gene
Location
4 : 28813384-28964003 : positive

Family Information

Homologous gene family
HOM03P000004
(1817 genes in 37 species)
specific family
Orthologous gene family
ORTHO03P003318
(24 genes in 4 species)
specific family
Duplication type
Tandem duplicate

Descriptions

gene_descr
Eph receptor A7

Identifiers

Type Value
UniprotQ61772
MGI95276

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006468
IEA
Genome Projectprotein phosphorylation
GO:0006915
IEA
Genome Projectapoptotic process
GO:0007169
IEA
Genome Projecttransmembrane receptor protein tyrosine kinase signaling pathway
GO:0007275
IEA
Genome Projectmulticellular organismal development
GO:0007399
IEA
Genome Projectnervous system development
GO:0007420
IMP
Genome Projectbrain development
GO:0014067
IDA
Genome Projectnegative regulation of phosphatidylinositol 3-kinase signaling
GO:0016310
ISS
IEA
Genome Projectphosphorylation
GO:0018108
IEA
Genome Projectpeptidyl-tyrosine phosphorylation
GO:0022407
IDA
Genome Projectregulation of cell-cell adhesion
GO:0031290
IMP
Genome Projectretinal ganglion cell axon guidance
GO:0031952
IDA
Genome Projectregulation of protein autophosphorylation
GO:0043065
IEA
Genome Projectpositive regulation of apoptotic process
GO:0043281
IDA
Genome Projectregulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043525
IMP
Genome Projectpositive regulation of neuron apoptotic process
GO:0048013
IDA
ISO
IEA
Genome Projectephrin receptor signaling pathway
GO:0048668
IDA
Genome Projectcollateral sprouting
GO:0048671
IDA
Genome Projectnegative regulation of collateral sprouting
GO:0048755
IMP
Genome Projectbranching morphogenesis of a nerve
GO:0050730
IDA
ISO
IEA
Genome Projectregulation of peptidyl-tyrosine phosphorylation
GO:0050919
IDA
Genome Projectnegative chemotaxis
GO:0051964
IMP
Genome Projectnegative regulation of synapse assembly
GO:0070372
ISS, ISO
IEA
Genome Projectregulation of ERK1 and ERK2 cascade
GO:0072178
IGI
Genome Projectnephric duct morphogenesis

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000166
IEA
Genome Projectnucleotide binding
GO:0004672
IEA
Genome Projectprotein kinase activity
GO:0004713
IEA
Genome Projectprotein tyrosine kinase activity
GO:0004714
IEA
Genome Projecttransmembrane receptor protein tyrosine kinase activity
GO:0005003
IEA
Genome Projectephrin receptor activity
GO:0005004
IDA
Genome ProjectGPI-linked ephrin receptor activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0005524
IEA
Genome ProjectATP binding
GO:0008046
IMP
Genome Projectaxon guidance receptor activity
GO:0016301
IEA
Genome Projectkinase activity
GO:0016740
IEA
Genome Projecttransferase activity
GO:0045499
IDA
Genome Projectchemorepellent activity
GO:0046875
IEA
Genome Projectephrin receptor binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005886
IEA
Genome Projectplasma membrane
GO:0005887
IC, IEA
Genome Projectintegral component of plasma membrane
GO:0016020
IEA
Genome Projectmembrane
GO:0016021
IEA
Genome Projectintegral component of membrane
GO:0030425
IEA
Genome Projectdendrite
GO:0031594
IEA
Genome Projectneuromuscular junction
GO:0043025
IEA
Genome Projectneuronal cell body
GO:0045211
IEA
Genome Projectpostsynaptic membrane

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000719Protein kinase domain
IPR001090Ephrin receptor ligand binding domain
IPR001245Serine-threonine/tyrosine-protein kinase catalytic domain
IPR001426Tyrosine-protein kinase, receptor class V, conserved site
IPR001660Sterile alpha motif domain
IPR003961Fibronectin type III
IPR008266Tyrosine-protein kinase, active site
IPR008979Galactose-binding domain-like
IPR009030Growth factor receptor cysteine-rich domain
IPR011009Protein kinase-like domain
IPR013761Sterile alpha motif/pointed domain
IPR013783Immunoglobulin-like fold
IPR016257Ephrin receptor type-A /type-B
IPR017441Protein kinase, ATP binding site
IPR020635Tyrosine-protein kinase, catalytic domain
IPR027936Ephrin receptor, transmembrane domain

No MapMan annotations defined for this gene.