Gene: ENSMUSG00000028284 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000028284
Transcript Identifier
ENSMUST00000037607
Gene Type
Coding gene
Location
4 : 31964263-32019681 : positive

Family Information

Homologous gene family
HOM03P000004
(1817 genes in 37 species)
specific family
Orthologous gene family
ORTHO03P039463
(3 genes in 3 species)
specific family
Duplication type
Tandem duplicate

Descriptions

gene_descr
mitogen-activated protein kinase kinase kinase 7

Identifiers

Type Value
UniprotQ923A8
MGI1346877

Toolbox

Explore

Create

View

Browse

 

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000165
IDA
Genome ProjectMAPK cascade
GO:0000186
IEA
Genome Projectactivation of MAPKK activity
GO:0000187
IEA
Genome Projectactivation of MAPK activity
GO:0001525
IMP
Genome Projectangiogenesis
GO:0001841
IMP
Genome Projectneural tube formation
GO:0002726
IEA
Genome Projectpositive regulation of T cell cytokine production
GO:0006468
IDA
IEA
Genome Projectprotein phosphorylation
GO:0007165
IEA
Genome Projectsignal transduction
GO:0007179
IMP
Genome Projecttransforming growth factor beta receptor signaling pathway
GO:0007250
IEA
Genome Projectactivation of NF-kappaB-inducing kinase activity
GO:0007252
IGI
IEA
Genome ProjectI-kappaB phosphorylation
GO:0007254
IEA
Genome ProjectJNK cascade
GO:0016310
IEA
Genome Projectphosphorylation
GO:0032743
IEA
Genome Projectpositive regulation of interleukin-2 production
GO:0043123
IGI
IEA
Genome Projectpositive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043507
IEA
Genome Projectpositive regulation of JUN kinase activity
GO:0043966
IEA
Genome Projecthistone H3 acetylation
GO:0046330
IGI
Genome Projectpositive regulation of JNK cascade
GO:0051403
IEA
Genome Projectstress-activated MAPK cascade
GO:1902443
IGI
Genome Projectnegative regulation of ripoptosome assembly involved in necroptotic process
GO:2000377
IMP
Genome Projectregulation of reactive oxygen species metabolic process
GO:2001234
IMP, IGI
Genome Projectnegative regulation of apoptotic signaling pathway

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000287
IEA
Genome Projectmagnesium ion binding
GO:0004672
IEA
Genome Projectprotein kinase activity
GO:0004674
IEA
Genome Projectprotein serine/threonine kinase activity
GO:0004708
IDA
Genome ProjectMAP kinase kinase activity
GO:0004709
IEA
Genome ProjectMAP kinase kinase kinase activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0005524
IEA
Genome ProjectATP binding
GO:0016301
IEA
Genome Projectkinase activity
GO:0097110
ISO
IEA
Genome Projectscaffold protein binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IEA
Genome Projectnucleus
GO:0005654
IEA
Genome Projectnucleoplasm
GO:0005671
IEA
Genome ProjectAda2/Gcn5/Ada3 transcription activator complex
GO:0005737
IEA
Genome Projectcytoplasm
GO:0008385
IEA
Genome ProjectIkappaB kinase complex
GO:0097481
IDA
Genome Projectneuronal postsynaptic density

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000719Protein kinase domain
IPR001245Serine-threonine/tyrosine-protein kinase catalytic domain
IPR008271Serine/threonine-protein kinase, active site
IPR011009Protein kinase-like domain
IPR017421Mitogen-activated protein (MAP) kinase kinase kinase 7
IPR017441Protein kinase, ATP binding site

No MapMan annotations defined for this gene.