Gene: ENSMUSG00000028224 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000028224
Transcript Identifier
ENSMUST00000029879
Gene Type
Coding gene
Location
4 : 15958074-15992461 : positive

Family Information

Homologous gene family
HOM03P011174
(7 genes in 7 species)
specific family

Descriptions

gene_descr
nibrin

Identifiers

Type Value
UniprotQ9R207
MGI1351625

Toolbox

Explore

Create

View

Browse

 

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000077
ISO
IEA
Genome ProjectDNA damage checkpoint
GO:0000723
ISS, ISO
IEA
Genome Projecttelomere maintenance
GO:0001701
IMP
Genome Projectin utero embryonic development
GO:0001832
IMP
Genome Projectblastocyst growth
GO:0006281
IEA
Genome ProjectDNA repair
GO:0006302
ISS, ISO
IEA
Genome Projectdouble-strand break repair
GO:0006974
IEA
Genome Projectcellular response to DNA damage stimulus
GO:0007049
IEA
Genome Projectcell cycle
GO:0007093
ISS, ISO
IEA
Genome Projectmitotic cell cycle checkpoint
GO:0007095
IMP
ISS, ISO
IEA
Genome Projectmitotic G2 DNA damage checkpoint
GO:0008283
IMP
Genome Projectcell proliferation
GO:0031954
ISO
IEA
Genome Projectpositive regulation of protein autophosphorylation
GO:0032508
ISO
IEA
Genome ProjectDNA duplex unwinding
GO:0033674
ISO
IEA
Genome Projectpositive regulation of kinase activity
GO:0045190
IDA
Genome Projectisotype switching
GO:0048145
ISS
Genome Projectregulation of fibroblast proliferation
GO:0050885
IMP
Genome Projectneuromuscular process controlling balance
GO:0051321
IEA
Genome Projectmeiotic cell cycle
GO:0097193
IMP
Genome Projectintrinsic apoptotic signaling pathway

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0003684
IDA
Genome Projectdamaged DNA binding
GO:0004003
ISO
IEA
Genome ProjectATP-dependent DNA helicase activity
GO:0008134
ISS, ISO
IEA
Genome Projecttranscription factor binding
GO:0047485
ISS, ISO
IEA
Genome Projectprotein N-terminus binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000781
IEA
Genome Projectchromosome, telomeric region
GO:0000784
ISO
IEA
Genome Projectnuclear chromosome, telomeric region
GO:0005634
IDA
ISO
IEA
Genome Projectnucleus
GO:0005657
IDA
Genome Projectreplication fork
GO:0005694
IEA
Genome Projectchromosome
GO:0005730
ISO
IEA
Genome Projectnucleolus
GO:0016605
ISO
IEA
Genome ProjectPML body
GO:0030870
ISS, ISO
IEA
Genome ProjectMre11 complex
GO:0035861
ISO
IEA
Genome Projectsite of double-strand break
GO:0042405
ISS, ISO
IEA
Genome Projectnuclear inclusion body

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000253Forkhead-associated (FHA) domain
IPR001357BRCT domain
IPR008984SMAD/FHA domain
IPR013908DNA repair Nbs1, C-terminal
IPR016592Nibrin
IPR032429Nibrin, second BRCT domain

No MapMan annotations defined for this gene.