Gene: ENSMUSG00000028086 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000028086
Transcript Identifier
ENSMUST00000107678
Gene Type
Coding gene
Location
3 : 84903570-84977541 : positive

Family Information

Homologous gene family
HOM03P000003
(2229 genes in 39 species)
specific family
Duplication type
Tandem duplicate

Descriptions

gene_descr
F-box and WD-40 domain protein 7

Identifiers

Type Value
UniprotD3YUA5
MGI1354695

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001570
IMP
Genome Projectvasculogenesis
GO:0006355
IDA
Genome Projectregulation of transcription, DNA-templated
GO:0006974
ISO
IEA
Genome Projectcellular response to DNA damage stimulus
GO:0007062
ISO
IEA
Genome Projectsister chromatid cohesion
GO:0007219
IDA
Genome ProjectNotch signaling pathway
GO:0016567
ISO, ISA
IEA
Genome Projectprotein ubiquitination
GO:0030324
IMP
Genome Projectlung development
GO:0031146
ISO, IBA
IEA
Genome ProjectSCF-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0031398
ISO
IEA
Genome Projectpositive regulation of protein ubiquitination
GO:0032876
ISO
IEA
Genome Projectnegative regulation of DNA endoreduplication
GO:0034644
ISO
IEA
Genome Projectcellular response to UV
GO:0045741
ISO
IEA
Genome Projectpositive regulation of epidermal growth factor-activated receptor activity
GO:0050821
ISO
IEA
Genome Projectprotein stabilization
GO:0051443
ISO
IEA
Genome Projectpositive regulation of ubiquitin-protein transferase activity
GO:0070374
ISO
IEA
Genome Projectpositive regulation of ERK1 and ERK2 cascade
GO:1901800
ISO
IEA
Genome Projectpositive regulation of proteasomal protein catabolic process
GO:1903146
ISO
Genome Projectregulation of mitophagy
GO:1903378
ISO
IEA
Genome Projectpositive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway
GO:1903955
ISO
Genome Projectpositive regulation of protein targeting to mitochondrion
GO:2000060
ISO
IEA
Genome Projectpositive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0003700
IDA
Genome Projecttranscription factor activity, sequence-specific DNA binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0030332
ISO
IEA
Genome Projectcyclin binding
GO:0030674
ISO
IEA
Genome Projectprotein binding, bridging
GO:0031625
ISO
IEA
Genome Projectubiquitin protein ligase binding
GO:0042802
ISO
IEA
Genome Projectidentical protein binding
GO:0097027
ISO
IEA
Genome Projectubiquitin-protein transferase activator activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IDA
TAS
Genome Projectnucleus
GO:0005654
ISO
Genome Projectnucleoplasm
GO:0005730
ISO
Genome Projectnucleolus
GO:0005737
ISO
TAS, IEA
Genome Projectcytoplasm
GO:0005783
IDA
Genome Projectendoplasmic reticulum
GO:0005794
IDA
Genome ProjectGolgi apparatus
GO:0019005
ISO
IEA
Genome ProjectSCF ubiquitin ligase complex
GO:0043234
ISO
IEA
Genome Projectprotein complex
GO:1990452
ISO
IEA
Genome ProjectParkin-FBXW7-Cul1 ubiquitin ligase complex

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR001680WD40 repeat
IPR001810F-box domain
IPR015943WD40/YVTN repeat-like-containing domain
IPR017986WD40-repeat-containing domain
IPR019775WD40 repeat, conserved site
IPR020472G-protein beta WD-40 repeat

No MapMan annotations defined for this gene.