Gene: ENSMUSG00000028017 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000028017
Transcript Identifier
ENSMUST00000029653
Gene Type
Coding gene
Location
3 : 129678320-129754964 : negative

Family Information

Homologous gene family
HOM03P001101
(58 genes in 4 species)
specific family
Orthologous gene family
ORTHO03P063369
(2 genes in 2 species)
specific family

Descriptions

gene_descr
epidermal growth factor

Identifiers

Type Value
UniprotP01132
MGI95290

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000186
IDA
Genome Projectactivation of MAPKK activity
GO:0001525
ISO
IEA
Genome Projectangiogenesis
GO:0007173
IDA, IGI
Genome Projectepidermal growth factor receptor signaling pathway
GO:0007262
IDA
Genome ProjectSTAT protein import into nucleus
GO:0008284
IDA, IGI
ISO
IEA
Genome Projectpositive regulation of cell proliferation
GO:0010800
ISO
IEA
Genome Projectpositive regulation of peptidyl-threonine phosphorylation
GO:0018108
IDA
Genome Projectpeptidyl-tyrosine phosphorylation
GO:0021940
IDA
Genome Projectpositive regulation of cerebellar granule cell precursor proliferation
GO:0035413
ISO
IEA
Genome Projectpositive regulation of catenin import into nucleus
GO:0042327
ISO
IEA
Genome Projectpositive regulation of phosphorylation
GO:0043388
IDA
Genome Projectpositive regulation of DNA binding
GO:0043406
ISO
IEA
Genome Projectpositive regulation of MAP kinase activity
GO:0045741
ISO
IEA
Genome Projectpositive regulation of epidermal growth factor-activated receptor activity
GO:0045840
ISO
IEA
Genome Projectpositive regulation of mitotic nuclear division
GO:0045893
ISO
IEA
Genome Projectpositive regulation of transcription, DNA-templated
GO:0048754
IDA
Genome Projectbranching morphogenesis of an epithelial tube
GO:0050730
IDA
Genome Projectregulation of peptidyl-tyrosine phosphorylation
GO:0050731
IDA
Genome Projectpositive regulation of peptidyl-tyrosine phosphorylation
GO:0051048
ISO
IEA
Genome Projectnegative regulation of secretion
GO:0051223
ISO
Genome Projectregulation of protein transport
GO:0060749
IGI
Genome Projectmammary gland alveolus development
GO:0070371
ISO
IEA
Genome ProjectERK1 and ERK2 cascade
GO:0090279
ISO
IEA
Genome Projectregulation of calcium ion import
GO:0090370
IDA
Genome Projectnegative regulation of cholesterol efflux
GO:1900127
ISO
IEA
Genome Projectpositive regulation of hyaluronan biosynthetic process
GO:2000008
ISO
IEA
Genome Projectregulation of protein localization to cell surface
GO:2000060
IDA
Genome Projectpositive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005154
IDA
Genome Projectepidermal growth factor receptor binding
GO:0005509
IEA
Genome Projectcalcium ion binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0008083
ISO
IEA
Genome Projectgrowth factor activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005576
TAS
Genome Projectextracellular region
GO:0005615
IDA
ISO
IEA
Genome Projectextracellular space
GO:0005765
ISO
IEA
Genome Projectlysosomal membrane
GO:0005886
IDA
TAS
Genome Projectplasma membrane
GO:0016020
IEA
Genome Projectmembrane
GO:0016021
IEA
Genome Projectintegral component of membrane
GO:0070062
ISO
IEA
Genome Projectextracellular exosome

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000033LDLR class B repeat
IPR000152EGF-type aspartate/asparagine hydroxylation site
IPR000742EGF-like domain
IPR001881EGF-like calcium-binding domain
IPR009030Growth factor receptor cysteine-rich domain
IPR011042Six-bladed beta-propeller, TolB-like
IPR013032EGF-like, conserved site
IPR016317Pro-epidermal growth factor
IPR018097EGF-like calcium-binding, conserved site

No MapMan annotations defined for this gene.