Gene: ENSMUSG00000028001 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000028001
Transcript Identifier
ENSMUST00000166581
Gene Type
Coding gene
Location
3 : 83026215-83033410 : positive

Family Information

Homologous gene family
HOM03P000911
(65 genes in 6 species)
specific family
Orthologous gene family
ORTHO03P066965
(2 genes in 2 species)
specific family
Duplication type
Tandem duplicate

Descriptions

gene_descr
fibrinogen alpha chain

Identifiers

Type Value
UniprotE9PV24
MGI1316726

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0002250
IEA
Genome Projectadaptive immune response
GO:0002376
IEA
Genome Projectimmune system process
GO:0006461
ISO
Genome Projectprotein complex assembly
GO:0006953
IEA
Genome Projectacute-phase response
GO:0007160
ISO
IEA
Genome Projectcell-matrix adhesion
GO:0007165
IEA
Genome Projectsignal transduction
GO:0007596
IMP
IEA
Genome Projectblood coagulation
GO:0007599
IEA
Genome Projecthemostasis
GO:0030168
IEA
Genome Projectplatelet activation
GO:0031639
ISO
Genome Projectplasminogen activation
GO:0032355
IEA
Genome Projectresponse to estradiol
GO:0033595
IEA
Genome Projectresponse to genistein
GO:0034116
ISO
IEA
Genome Projectpositive regulation of heterotypic cell-cell adhesion
GO:0042730
ISO
Genome Projectfibrinolysis
GO:0043152
ISO
IEA
Genome Projectinduction of bacterial agglutination
GO:0043278
IEA
Genome Projectresponse to morphine
GO:0043623
ISO
IEA
Genome Projectcellular protein complex assembly
GO:0045087
IEA
Genome Projectinnate immune response
GO:0045907
ISO
IEA
Genome Projectpositive regulation of vasoconstriction
GO:0045921
ISO
IEA
Genome Projectpositive regulation of exocytosis
GO:0046898
IEA
Genome Projectresponse to cycloheximide
GO:0050714
ISO
IEA
Genome Projectpositive regulation of protein secretion
GO:0051258
ISO
IEA
Genome Projectprotein polymerization
GO:0051592
ISO
IEA
Genome Projectresponse to calcium ion
GO:0070374
ISO
IEA
Genome Projectpositive regulation of ERK1 and ERK2 cascade
GO:0070527
ISO
IEA
Genome Projectplatelet aggregation
GO:0071345
IEA
Genome Projectcellular response to cytokine stimulus
GO:0071354
IEA
Genome Projectcellular response to interleukin-6
GO:0071407
IEA
Genome Projectcellular response to organic cyclic compound
GO:0072377
ISO
IEA
Genome Projectblood coagulation, common pathway
GO:0072378
ISO
Genome Projectblood coagulation, fibrin clot formation
GO:0090277
ISO
IEA
Genome Projectpositive regulation of peptide hormone secretion
GO:0097421
IEA
Genome Projectliver regeneration
GO:1902042
ISO
IEA
Genome Projectnegative regulation of extrinsic apoptotic signaling pathway via death domain receptors
GO:1990643
IEA
Genome Projectcellular response to granulocyte colony-stimulating factor
GO:2000352
ISO
IEA
Genome Projectnegative regulation of endothelial cell apoptotic process

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005102
ISO
IEA
Genome Projectreceptor binding
GO:0005198
ISO
IEA
Genome Projectstructural molecule activity
GO:0030674
IEA
Genome Projectprotein binding, bridging
GO:0050839
ISO
IEA
Genome Projectcell adhesion molecule binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005576
IEA
Genome Projectextracellular region
GO:0005577
ISO
IEA
Genome Projectfibrinogen complex
GO:0005615
ISO
IEA
Genome Projectextracellular space
GO:0005737
IEA
Genome Projectcytoplasm
GO:0005791
IEA
Genome Projectrough endoplasmic reticulum
GO:0005938
IDA
Genome Projectcell cortex
GO:0009897
ISO
IEA
Genome Projectexternal side of plasma membrane
GO:0009986
ISO
IEA
Genome Projectcell surface
GO:0031091
ISO
IEA
Genome Projectplatelet alpha granule
GO:0031982
IEA
Genome Projectvesicle
GO:0070062
ISO
IEA
Genome Projectextracellular exosome
GO:0072562
ISO
IEA
Genome Projectblood microparticle
GO:1903561
ISO
Genome Projectextracellular vesicle

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR002181Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain
IPR012290Fibrinogen, alpha/beta/gamma chain, coiled coil domain
IPR014715Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 2
IPR014716Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1
IPR020837Fibrinogen, conserved site
IPR021996Fibrinogen alpha C domain

No MapMan annotations defined for this gene.