Gene: ENSMUSG00000027859 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000027859
Transcript Identifier
ENSMUST00000106925
Gene Type
Coding gene
Location
3 : 102509776-102520848 : positive

Family Information

Homologous gene family
HOM03P010566
(8 genes in 2 species)
specific family
Orthologous gene family
ORTHO03P067019
(2 genes in 2 species)
specific family
Duplication type
Block duplicate

Descriptions

gene_descr
nerve growth factor

Identifiers

Type Value
UniprotQ6LDU8
MGI97321

Toolbox

Explore

Create

View

Browse

 

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0007169
IBA
Genome Projecttransmembrane receptor protein tyrosine kinase signaling pathway
GO:0007267
IBA
Genome Projectcell-cell signaling
GO:0007422
IMP
Genome Projectperipheral nervous system development
GO:0008625
ISO
IEA
Genome Projectextrinsic apoptotic signaling pathway via death domain receptors
GO:0010628
IGI
ISO
IEA
Genome Projectpositive regulation of gene expression
GO:0010951
ISO
Genome Projectnegative regulation of endopeptidase activity
GO:0010976
IDA, IGI
Genome Projectpositive regulation of neuron projection development
GO:0014042
IDA, IGI
Genome Projectpositive regulation of neuron maturation
GO:0019233
IMP
Genome Projectsensory perception of pain
GO:0031398
IDA
Genome Projectpositive regulation of protein ubiquitination
GO:0031954
ISO
Genome Projectpositive regulation of protein autophosphorylation
GO:0035556
IDA
Genome Projectintracellular signal transduction
GO:0038180
IDA, IGI
Genome Projectnerve growth factor signaling pathway
GO:0043524
IGI
Genome Projectnegative regulation of neuron apoptotic process
GO:0045664
IDA
Genome Projectregulation of neuron differentiation
GO:0045773
IDA, IMP
Genome Projectpositive regulation of axon extension
GO:0046928
IGI
Genome Projectregulation of neurotransmitter secretion
GO:0048672
IDA
Genome Projectpositive regulation of collateral sprouting
GO:0048812
ISO, IBA
IEA
Genome Projectneuron projection morphogenesis
GO:0051091
ISO
Genome Projectpositive regulation of sequence-specific DNA binding transcription factor activity
GO:0051279
IGI
Genome Projectregulation of release of sequestered calcium ion into cytosol
GO:0051388
ISO
Genome Projectpositive regulation of neurotrophin TRK receptor signaling pathway
GO:0051402
IMP
Genome Projectneuron apoptotic process
GO:0097192
IDA
Genome Projectextrinsic apoptotic signaling pathway in absence of ligand

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005057
IDA
Genome Projectreceptor signaling protein activity
GO:0005102
IEA
Genome Projectreceptor binding
GO:0005163
ISO, IBA
IEA
Genome Projectnerve growth factor receptor binding
GO:0008083
IBA
IEA
Genome Projectgrowth factor activity
GO:0008191
ISO
IEA
Genome Projectmetalloendopeptidase inhibitor activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0016023
IBA
Genome Projectcytoplasmic membrane-bounded vesicle

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR002072Nerve growth factor-related
IPR019846Nerve growth factor conserved site
IPR020408Nerve growth factor-like
IPR020425Nerve growth factor, beta subunit
IPR020437Nerve growth factor, beta subunit, mammalian
IPR029034Cystine-knot cytokine

No MapMan annotations defined for this gene.