Gene: ENSMUSG00000027843 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000027843
Transcript Identifier
ENSMUST00000029433
Gene Type
Coding gene
Location
3 : 103860404-103912040 : positive

Family Information

Homologous gene family
HOM03P000197
(172 genes in 24 species)
specific family
Orthologous gene family
ORTHO03P068393
(2 genes in 2 species)
specific family
Duplication type
Block duplicate

Descriptions

gene_descr
protein tyrosine phosphatase, non-receptor type 22 (lymphoid)

Identifiers

Type Value
UniprotP29352
MGI107170

Toolbox

Explore

Create

View

Browse

 

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0002230
IMP
Genome Projectpositive regulation of defense response to virus by host
GO:0002376
IEA
Genome Projectimmune system process
GO:0002685
IMP
Genome Projectregulation of leukocyte migration
GO:0006470
IMP
ISO
IEA
Genome Projectprotein dephosphorylation
GO:0006914
IEA
Genome Projectautophagy
GO:0010507
ISO
Genome Projectnegative regulation of autophagy
GO:0010628
IMP
ISO
Genome Projectpositive regulation of gene expression
GO:0010629
IMP
ISO
Genome Projectnegative regulation of gene expression
GO:0016311
IEA
Genome Projectdephosphorylation
GO:0030217
IMP
Genome ProjectT cell differentiation
GO:0031663
ISO
Genome Projectlipopolysaccharide-mediated signaling pathway
GO:0032481
ISO
Genome Projectpositive regulation of type I interferon production
GO:0032720
IMP
ISO
Genome Projectnegative regulation of tumor necrosis factor production
GO:0032817
ISS, ISO
Genome Projectregulation of natural killer cell proliferation
GO:0034141
IMP
ISO
Genome Projectpositive regulation of toll-like receptor 3 signaling pathway
GO:0034145
IMP
ISO
Genome Projectpositive regulation of toll-like receptor 4 signaling pathway
GO:0034157
IMP
Genome Projectpositive regulation of toll-like receptor 7 signaling pathway
GO:0034165
IMP
Genome Projectpositive regulation of toll-like receptor 9 signaling pathway
GO:0035335
ISO
Genome Projectpeptidyl-tyrosine dephosphorylation
GO:0035549
IMP
Genome Projectpositive regulation of interferon-beta secretion
GO:0035644
IDA
Genome Projectphosphoanandamide dephosphorylation
GO:0042993
IMP
Genome Projectpositive regulation of transcription factor import into nucleus
GO:0043508
ISO
Genome Projectnegative regulation of JUN kinase activity
GO:0050852
IMP
Genome ProjectT cell receptor signaling pathway
GO:0050856
IEA
Genome Projectregulation of T cell receptor signaling pathway
GO:0050860
ISS, ISO
Genome Projectnegative regulation of T cell receptor signaling pathway
GO:0050868
IMP
ISO
Genome Projectnegative regulation of T cell activation
GO:0070374
IMP
ISO
Genome Projectpositive regulation of ERK1 and ERK2 cascade
GO:0070433
IMP
ISO
Genome Projectnegative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway
GO:0071663
IMP
Genome Projectpositive regulation of granzyme B production
GO:1900165
IMP
ISO
Genome Projectnegative regulation of interleukin-6 secretion
GO:1901222
IMP
ISO
Genome Projectregulation of NIK/NF-kappaB signaling
GO:1902523
IMP
ISO
Genome Projectpositive regulation of protein K63-linked ubiquitination
GO:1902715
ISO
Genome Projectpositive regulation of interferon-gamma secretion
GO:1902741
IMP
Genome Projectpositive regulation of interferon-alpha secretion
GO:1903753
IMP
ISO
Genome Projectnegative regulation of p38MAPK cascade
GO:2000483
IMP
ISO
Genome Projectnegative regulation of interleukin-8 secretion
GO:2000566
IMP
Genome Projectpositive regulation of CD8-positive, alpha-beta T cell proliferation
GO:0002577
IMP
Genome Projectregulation of antigen processing and presentation

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004721
IEA
Genome Projectphosphoprotein phosphatase activity
GO:0004725
ISS, ISO
IEA
Genome Projectprotein tyrosine phosphatase activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0016787
IEA
Genome Projecthydrolase activity
GO:0016791
ISO
IEA
Genome Projectphosphatase activity
GO:0017124
IPI
Genome ProjectSH3 domain binding
GO:0019900
IPI
Genome Projectkinase binding
GO:0031625
ISO
Genome Projectubiquitin protein ligase binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IDA
ISO
Genome Projectnucleus
GO:0005737
IDA
ISO
IEA
Genome Projectcytoplasm
GO:0009898
IDA
ISO
Genome Projectcytoplasmic side of plasma membrane
GO:0048471
ISS, ISO
Genome Projectperinuclear region of cytoplasm

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000242PTP type protein phosphatase
IPR000387Tyrosine specific protein phosphatases domain
IPR016130Protein-tyrosine phosphatase, active site
IPR016276Non-receptor tyrosine-protein phosphatase 22
IPR029021Protein-tyrosine phosphatase-like

No MapMan annotations defined for this gene.