Gene: ENSMUSG00000027720 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000027720
Transcript Identifier
ENSMUST00000029275
Gene Type
Coding gene
Location
3 : 37121104-37125906 : negative

Family Information

Homologous gene family
HOM03P118620
(orphan gene)
specific family

Descriptions

gene_descr
interleukin 2

Identifiers

Type Value
UniprotP04351
MGI96548

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001933
IEA
Genome Projectnegative regulation of protein phosphorylation
GO:0001934
IEA
Genome Projectpositive regulation of protein phosphorylation
GO:0002250
IEA
Genome Projectadaptive immune response
GO:0002376
IEA
Genome Projectimmune system process
GO:0002903
ISO
IEA
Genome Projectnegative regulation of B cell apoptotic process
GO:0006955
IEA
Genome Projectimmune response
GO:0007186
IEA
Genome ProjectG-protein coupled receptor signaling pathway
GO:0007204
IEA
Genome Projectpositive regulation of cytosolic calcium ion concentration
GO:0007205
IEA
Genome Projectprotein kinase C-activating G-protein coupled receptor signaling pathway
GO:0030890
ISO, IBA
IEA
Genome Projectpositive regulation of B cell proliferation
GO:0032729
IDA
Genome Projectpositive regulation of interferon-gamma production
GO:0032740
ISO
IEA
Genome Projectpositive regulation of interleukin-17 production
GO:0042102
IDA, IMP
IEA
Genome Projectpositive regulation of T cell proliferation
GO:0042104
IDA, IMP
ISO
IEA
Genome Projectpositive regulation of activated T cell proliferation
GO:0042523
IDA
ISO
IEA
Genome Projectpositive regulation of tyrosine phosphorylation of Stat5 protein
GO:0045582
IEA
Genome Projectpositive regulation of T cell differentiation
GO:0045591
IEA
Genome Projectpositive regulation of regulatory T cell differentiation
GO:0045822
IEA
Genome Projectnegative regulation of heart contraction
GO:0045944
IDA
Genome Projectpositive regulation of transcription from RNA polymerase II promoter
GO:0046013
IMP
Genome Projectregulation of T cell homeostatic proliferation
GO:0048304
IMP
Genome Projectpositive regulation of isotype switching to IgG isotypes
GO:0050672
IMP
Genome Projectnegative regulation of lymphocyte proliferation
GO:0050728
IMP
Genome Projectnegative regulation of inflammatory response
GO:0051024
IMP
Genome Projectpositive regulation of immunoglobulin secretion
GO:0060999
IEA
Genome Projectpositive regulation of dendritic spine development
GO:0097192
IDA
Genome Projectextrinsic apoptotic signaling pathway in absence of ligand

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005125
IDA, IMP
ISO
IEA
Genome Projectcytokine activity
GO:0005134
IDA
ISO
IEA
Genome Projectinterleukin-2 receptor binding
GO:0008083
IEA
Genome Projectgrowth factor activity
GO:0030246
IEA
Genome Projectcarbohydrate binding
GO:0031851
IEA
Genome Projectkappa-type opioid receptor binding
GO:0043208
IEA
Genome Projectglycosphingolipid binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005576
IEA
Genome Projectextracellular region
GO:0005615
IDA
IEA
Genome Projectextracellular space
GO:0005829
IEA
Genome Projectcytosol

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000779Interleukin-2
IPR009079Four-helical cytokine-like, core
IPR012351Four-helical cytokine, core
IPR030477Interleukin-2, conserved site

No MapMan annotations defined for this gene.