Gene: ENSMUSG00000027692 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000027692
Transcript Identifier
ENSMUST00000160307
Gene Type
Coding gene
Location
3 : 28263643-28667982 : positive

Family Information

Homologous gene family
HOM03P000001
(4368 genes in 39 species)
specific family
Orthologous gene family
ORTHO03P010340
(8 genes in 4 species)
specific family

Descriptions

gene_descr
TRAF2 and NCK interacting kinase

Identifiers

Type Value
UniprotB2RQ80
MGI1916264

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000165
IBA
Genome ProjectMAPK cascade
GO:0001934
ISO
IEA
Genome Projectpositive regulation of protein phosphorylation
GO:0002230
ISO
Genome Projectpositive regulation of defense response to virus by host
GO:0006468
ISO
IEA
Genome Projectprotein phosphorylation
GO:0007010
ISO
IEA
Genome Projectcytoskeleton organization
GO:0007256
ISO
IEA
Genome Projectactivation of JNKK activity
GO:0007346
IBA
Genome Projectregulation of mitotic cell cycle
GO:0030033
ISO
IEA
Genome Projectmicrovillus assembly
GO:0031098
IBA
Genome Projectstress-activated protein kinase signaling cascade
GO:0031532
ISO
IEA
Genome Projectactin cytoskeleton reorganization
GO:0032147
IBA
Genome Projectactivation of protein kinase activity
GO:0035556
ISO
IEA
Genome Projectintracellular signal transduction
GO:0042981
IBA
Genome Projectregulation of apoptotic process
GO:0046777
ISO
IEA
Genome Projectprotein autophosphorylation
GO:0048812
IBA
Genome Projectneuron projection morphogenesis
GO:0048814
ISO
IEA
Genome Projectregulation of dendrite morphogenesis
GO:0072659
ISO
IEA
Genome Projectprotein localization to plasma membrane

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000166
IEA
Genome Projectnucleotide binding
GO:0004672
ISO
IEA
Genome Projectprotein kinase activity
GO:0004674
ISO
IEA
Genome Projectprotein serine/threonine kinase activity
GO:0005524
IEA
Genome ProjectATP binding
GO:0008349
IBA
Genome ProjectMAP kinase kinase kinase kinase activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
ISO
IEA
Genome Projectnucleus
GO:0005654
ISO
IEA
Genome Projectnucleoplasm
GO:0005737
ISO, IBA
IEA
Genome Projectcytoplasm
GO:0005856
ISO
IEA
Genome Projectcytoskeleton
GO:0016324
ISO
IEA
Genome Projectapical plasma membrane
GO:0048471
ISO
Genome Projectperinuclear region of cytoplasm
GO:0055037
ISO
Genome Projectrecycling endosome
GO:0070062
ISO
IEA
Genome Projectextracellular exosome

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000719Protein kinase domain
IPR001180Citron homology (CNH) domain
IPR002290Serine/threonine/dual specificity protein kinase, catalytic domain
IPR008271Serine/threonine-protein kinase, active site
IPR011009Protein kinase-like domain
IPR017441Protein kinase, ATP binding site

No MapMan annotations defined for this gene.