Gene: ENSMUSG00000027478 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000027478
Transcript Identifier
ENSMUST00000109771
Gene Type
Coding gene
Location
2 : 153661431-153686399 : positive

Family Information

Homologous gene family
HOM03P007594
(11 genes in 6 species)
specific family
Orthologous gene family
ORTHO03P022893
(4 genes in 2 species)
specific family

Descriptions

gene_descr
DNA methyltransferase 3B

Identifiers

Type Value
UniprotQ3KR45
MGI1261819

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000122
IMP
ISO
IEA
Genome Projectnegative regulation of transcription from RNA polymerase II promoter
GO:0001666
IEA
Genome Projectresponse to hypoxia
GO:0006306
IMP, IGI
IEA
Genome ProjectDNA methylation
GO:0006346
IGI
Genome Projectmethylation-dependent chromatin silencing
GO:0006349
IMP
Genome Projectregulation of gene expression by genetic imprinting
GO:0009636
IEA
Genome Projectresponse to toxic substance
GO:0010212
IEA
Genome Projectresponse to ionizing radiation
GO:0010424
IEA
Genome ProjectDNA methylation on cytosine within a CG sequence
GO:0010468
IEA
Genome Projectregulation of gene expression
GO:0010628
ISO
IEA
Genome Projectpositive regulation of gene expression
GO:0014823
IEA
Genome Projectresponse to activity
GO:0031000
IEA
Genome Projectresponse to caffeine
GO:0031503
IDA
Genome Projectprotein complex localization
GO:0032259
IEA
Genome Projectmethylation
GO:0032355
IEA
Genome Projectresponse to estradiol
GO:0033189
IEA
Genome Projectresponse to vitamin A
GO:0042220
IEA
Genome Projectresponse to cocaine
GO:0042493
IEA
Genome Projectresponse to drug
GO:0045666
IEA
Genome Projectpositive regulation of neuron differentiation
GO:0045892
IEA
Genome Projectnegative regulation of transcription, DNA-templated
GO:0046498
IEA
Genome ProjectS-adenosylhomocysteine metabolic process
GO:0046499
IEA
Genome ProjectS-adenosylmethioninamine metabolic process
GO:0051571
ISO
IEA
Genome Projectpositive regulation of histone H3-K4 methylation
GO:0051573
ISO
IEA
Genome Projectnegative regulation of histone H3-K9 methylation
GO:0060821
IMP
Genome Projectinactivation of X chromosome by DNA methylation
GO:0071230
IDA
Genome Projectcellular response to amino acid stimulus
GO:0071455
IEA
Genome Projectcellular response to hyperoxia
GO:0071549
IEA
Genome Projectcellular response to dexamethasone stimulus
GO:0090116
ISO
Genome ProjectC-5 methylation of cytosine

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0003677
IDA
IEA
Genome ProjectDNA binding
GO:0003682
IEA
Genome Projectchromatin binding
GO:0003714
ISO
IEA
Genome Projecttranscription corepressor activity
GO:0003886
IDA, IGI
ISO
Genome ProjectDNA (cytosine-5-)-methyltransferase activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0008168
IEA
Genome Projectmethyltransferase activity
GO:0009008
IEA
Genome ProjectDNA-methyltransferase activity
GO:0016740
IEA
Genome Projecttransferase activity
GO:0042826
IEA
Genome Projecthistone deacetylase binding
GO:0045322
IEA
Genome Projectunmethylated CpG binding
GO:0051718
IEA
Genome ProjectDNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000792
IDA
Genome Projectheterochromatin
GO:0005634
IDA
ISO
IEA
Genome Projectnucleus
GO:0005654
ISO
IEA
Genome Projectnucleoplasm
GO:0005720
IDA
Genome Projectnuclear heterochromatin
GO:0005737
IEA
Genome Projectcytoplasm
GO:0043231
ISO
IEA
Genome Projectintracellular membrane-bounded organelle

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000313PWWP domain
IPR001525C-5 cytosine methyltransferase
IPR011011Zinc finger, FYVE/PHD-type
IPR018117DNA methylase, C-5 cytosine-specific, active site
IPR025766ADD domain
IPR029063S-adenosyl-L-methionine-dependent methyltransferase
IPR030488DNA (cytosine-5)-methyltransferase 3B

No MapMan annotations defined for this gene.