Gene: ENSMUSG00000027447 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000027447
Transcript Identifier
ENSMUST00000028938
Gene Type
Coding gene
Location
2 : 148871960-148875377 : negative

Family Information

Homologous gene family
HOM03P004570
(21 genes in 2 species)
specific family
Orthologous gene family
ORTHO03P067299
(2 genes in 2 species)
specific family
Duplication type
Tandem duplicate

Descriptions

gene_descr
cystatin C

Identifiers

Type Value
UniprotP21460
MGI102519

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001654
IEA
Genome Projecteye development
GO:0001666
IEA
Genome Projectresponse to hypoxia
GO:0001775
IEA
Genome Projectcell activation
GO:0006915
IEA
Genome Projectapoptotic process
GO:0006952
ISO
IEA
Genome Projectdefense response
GO:0006979
IEA
Genome Projectresponse to oxidative stress
GO:0007420
IEA
Genome Projectbrain development
GO:0007431
IEA
Genome Projectsalivary gland development
GO:0007566
IEA
Genome Projectembryo implantation
GO:0008284
IEA
Genome Projectpositive regulation of cell proliferation
GO:0008584
IEA
Genome Projectmale gonad development
GO:0009636
IEA
Genome Projectresponse to toxic substance
GO:0009743
IEA
Genome Projectresponse to carbohydrate
GO:0010035
IEA
Genome Projectresponse to inorganic substance
GO:0010466
ISO
IEA
Genome Projectnegative regulation of peptidase activity
GO:0010711
IEA
Genome Projectnegative regulation of collagen catabolic process
GO:0010716
IEA
Genome Projectnegative regulation of extracellular matrix disassembly
GO:0010951
ISO
Genome Projectnegative regulation of endopeptidase activity
GO:0014070
IEA
Genome Projectresponse to organic cyclic compound
GO:0031667
IEA
Genome Projectresponse to nutrient levels
GO:0032355
IEA
Genome Projectresponse to estradiol
GO:0034103
IEA
Genome Projectregulation of tissue remodeling
GO:0034599
IEA
Genome Projectcellular response to oxidative stress
GO:0042493
IEA
Genome Projectresponse to drug
GO:0042747
IEA
Genome Projectcircadian sleep/wake cycle, REM sleep
GO:0043067
IEA
Genome Projectregulation of programmed cell death
GO:0043206
ISO
IEA
Genome Projectextracellular fibril organization
GO:0045740
IEA
Genome Projectpositive regulation of DNA replication
GO:0045861
ISO
IEA
Genome Projectnegative regulation of proteolysis
GO:0048678
IEA
Genome Projectresponse to axon injury
GO:0060009
IEA
Genome ProjectSertoli cell development
GO:0060311
ISO
IEA
Genome Projectnegative regulation of elastin catabolic process
GO:0060313
IEA
Genome Projectnegative regulation of blood vessel remodeling
GO:0060548
IEA
Genome Projectnegative regulation of cell death
GO:0070301
IEA
Genome Projectcellular response to hydrogen peroxide

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001540
ISO
IEA
Genome Projectbeta-amyloid binding
GO:0002020
ISO
IEA
Genome Projectprotease binding
GO:0004866
ISO
IEA
Genome Projectendopeptidase inhibitor activity
GO:0004869
ISO
IEA
Genome Projectcysteine-type endopeptidase inhibitor activity
GO:0030414
IEA
Genome Projectpeptidase inhibitor activity
GO:0042802
ISO
IEA
Genome Projectidentical protein binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005576
ISO
IEA
Genome Projectextracellular region
GO:0005604
IEA
Genome Projectbasement membrane
GO:0005615
ISO
IEA
Genome Projectextracellular space
GO:0005737
IEA
Genome Projectcytoplasm
GO:0005764
IEA
Genome Projectlysosome
GO:0005771
IEA
Genome Projectmultivesicular body
GO:0005783
IEA
Genome Projectendoplasmic reticulum
GO:0030424
IEA
Genome Projectaxon
GO:0031965
IEA
Genome Projectnuclear membrane
GO:0031982
IEA
Genome Projectvesicle
GO:0042995
IEA
Genome Projectcell projection
GO:0043025
IEA
Genome Projectneuronal cell body
GO:0043292
IEA
Genome Projectcontractile fiber
GO:0048471
IEA
Genome Projectperinuclear region of cytoplasm
GO:0070062
ISO
IEA
Genome Projectextracellular exosome

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000010Cystatin domain
IPR018073Proteinase inhibitor I25, cystatin, conserved site
IPR027214Cystatin

No MapMan annotations defined for this gene.