Gene: ENSMUSG00000027381 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000027381
Transcript Identifier
ENSMUST00000110341
Gene Type
Coding gene
Location
2 : 128128633-128158329 : positive

Family Information

Homologous gene family
HOM03P048889
(2 genes in 2 species)
specific family

Descriptions

gene_descr
BCL2-like 11 (apoptosis facilitator)

Identifiers

Type Value
UniprotO54918
UniprotQ542N5
MGI1197519

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001701
IGI
Genome Projectin utero embryonic development
GO:0001776
IMP, IGI
Genome Projectleukocyte homeostasis
GO:0001782
IMP, IGI
Genome ProjectB cell homeostasis
GO:0001783
IGI
Genome ProjectB cell apoptotic process
GO:0001822
IGI
Genome Projectkidney development
GO:0002260
IMP, IGI
Genome Projectlymphocyte homeostasis
GO:0002262
IGI
Genome Projectmyeloid cell homeostasis
GO:0006915
IEA
Genome Projectapoptotic process
GO:0006919
ISO
IEA
Genome Projectactivation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0007160
IMP
Genome Projectcell-matrix adhesion
GO:0007283
IGI
Genome Projectspermatogenesis
GO:0007420
IEA
Genome Projectbrain development
GO:0008584
IGI
Genome Projectmale gonad development
GO:0008630
IGI
ISO
IEA
Genome Projectintrinsic apoptotic signaling pathway in response to DNA damage
GO:0009791
IGI
Genome Projectpost-embryonic development
GO:0010942
IEA
Genome Projectpositive regulation of cell death
GO:0030879
IMP
Genome Projectmammary gland development
GO:0032464
ISO
IEA
Genome Projectpositive regulation of protein homooligomerization
GO:0034976
IDA
ISO
IEA
Genome Projectresponse to endoplasmic reticulum stress
GO:0035148
IMP
Genome Projecttube formation
GO:0042475
IGI
Genome Projectodontogenesis of dentin-containing tooth
GO:0042981
IGI
Genome Projectregulation of apoptotic process
GO:0043029
IMP, IGI
Genome ProjectT cell homeostasis
GO:0043065
IMP, IGI
ISO
IEA
Genome Projectpositive regulation of apoptotic process
GO:0043280
IMP
Genome Projectpositive regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043525
IDA
Genome Projectpositive regulation of neuron apoptotic process
GO:0043583
IGI
Genome Projectear development
GO:0045787
IMP
Genome Projectpositive regulation of cell cycle
GO:0046620
IMP
Genome Projectregulation of organ growth
GO:0048066
IGI
Genome Projectdevelopmental pigmentation
GO:0048070
IGI
Genome Projectregulation of developmental pigmentation
GO:0048536
IGI
Genome Projectspleen development
GO:0048538
IGI
Genome Projectthymus development
GO:0048563
IMP
Genome Projectpost-embryonic organ morphogenesis
GO:0060139
IDA
Genome Projectpositive regulation of apoptotic process by virus
GO:0060154
IDA
Genome Projectcellular process regulating host cell cycle in response to virus
GO:0070242
IGI
Genome Projectthymocyte apoptotic process
GO:0090200
ISO
IEA
Genome Projectpositive regulation of release of cytochrome c from mitochondria
GO:0097192
IMP, IGI
Genome Projectextrinsic apoptotic signaling pathway in absence of ligand
GO:1902110
IGI
Genome Projectpositive regulation of mitochondrial membrane permeability involved in apoptotic process
GO:1902263
IGI
Genome Projectapoptotic process involved in embryonic digit morphogenesis
GO:2000271
ISO
IEA
Genome Projectpositive regulation of fibroblast apoptotic process
GO:2001244
ISO
IEA
Genome Projectpositive regulation of intrinsic apoptotic signaling pathway
GO:0007127
IBA
Genome Projectmeiosis I

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005515
IPI
Genome Projectprotein binding
GO:0008017
IDA
ISO
IEA
Genome Projectmicrotubule binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005737
IDA
Genome Projectcytoplasm
GO:0005739
IDA
IEA
Genome Projectmitochondrion
GO:0005829
ISO
IEA
Genome Projectcytosol
GO:0005874
ISO
IEA
Genome Projectmicrotubule
GO:0016020
IEA
Genome Projectmembrane
GO:0019898
IDA
Genome Projectextrinsic component of membrane
GO:0043231
IDA
Genome Projectintracellular membrane-bounded organelle
GO:0097140
ISO
IEA
Genome ProjectBIM-BCL-xl complex
GO:0097141
ISO
IEA
Genome ProjectBIM-BCL-2 complex

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR014771Apoptosis, Bim N-terminal
IPR015040Bcl-x interacting, BH3 domain
IPR017288Bcl-2-like protein 11

No MapMan annotations defined for this gene.