Gene: ENSMUSG00000027087 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000027087
Transcript Identifier
ENSMUST00000028499
Gene Type
Coding gene
Location
2 : 83724735-83803335 : positive

Family Information

Homologous gene family
HOM03P002672
(35 genes in 4 species)
specific family
Orthologous gene family
ORTHO03P009315
(9 genes in 4 species)
specific family
Duplication type
Block duplicate

Descriptions

gene_descr
integrin alpha V

Identifiers

Type Value
UniprotP43406
MGI96608

Toolbox

Explore

Create

View

Browse

 

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001525
IEA
Genome Projectangiogenesis
GO:0001568
IMP
Genome Projectblood vessel development
GO:0006954
TAS
Genome Projectinflammatory response
GO:0007155
ISS, ISO
IEA
Genome Projectcell adhesion
GO:0007160
ISO
TAS
Genome Projectcell-matrix adhesion
GO:0007229
IEA
Genome Projectintegrin-mediated signaling pathway
GO:0007275
IEA
Genome Projectmulticellular organismal development
GO:0008284
ISS, ISO
IEA
Genome Projectpositive regulation of cell proliferation
GO:0009566
NAS
Genome Projectfertilization
GO:0010745
ISS, ISO
IEA
Genome Projectnegative regulation of macrophage derived foam cell differentiation
GO:0010888
ISS, ISO
IEA
Genome Projectnegative regulation of lipid storage
GO:0016049
ISO
IEA
Genome Projectcell growth
GO:0016477
ISO
IEA
Genome Projectcell migration
GO:0030154
IEA
Genome Projectcell differentiation
GO:0030335
IMP
Genome Projectpositive regulation of cell migration
GO:0031589
ISO
IEA
Genome Projectcell-substrate adhesion
GO:0032369
ISS, ISO
IEA
Genome Projectnegative regulation of lipid transport
GO:0032490
TAS
Genome Projectdetection of molecule of bacterial origin
GO:0033690
IMP
Genome Projectpositive regulation of osteoblast proliferation
GO:0034113
ISO
IEA
Genome Projectheterotypic cell-cell adhesion
GO:0034446
ISO
IEA
Genome Projectsubstrate adhesion-dependent cell spreading
GO:0035262
NAS
Genome Projectgonad morphogenesis
GO:0035987
ISO
IEA
Genome Projectendodermal cell differentiation
GO:0038027
ISO
IEA
Genome Projectapolipoprotein A-I-mediated signaling pathway
GO:0042110
TAS
Genome ProjectT cell activation
GO:0043277
IMP
Genome Projectapoptotic cell clearance
GO:0043542
TAS
Genome Projectendothelial cell migration
GO:0045124
TAS
Genome Projectregulation of bone resorption
GO:0045715
ISS, ISO
IEA
Genome Projectnegative regulation of low-density lipoprotein particle receptor biosynthetic process
GO:0045785
ISS, ISO
IEA
Genome Projectpositive regulation of cell adhesion
GO:0046718
ISO
Genome Projectviral entry into host cell
GO:0048041
NAS
Genome Projectfocal adhesion assembly
GO:0050748
ISS, ISO
IEA
Genome Projectnegative regulation of lipoprotein metabolic process
GO:0050764
ISS, ISO
NAS, IEA
Genome Projectregulation of phagocytosis
GO:0050919
ISO
IEA
Genome Projectnegative chemotaxis
GO:0051209
TAS
Genome Projectrelease of sequestered calcium ion into cytosol
GO:0060707
TAS
Genome Projecttrophoblast giant cell differentiation
GO:0070371
IDA
Genome ProjectERK1 and ERK2 cascade
GO:0070588
ISO
IEA
Genome Projectcalcium ion transmembrane transport
GO:0071731
TAS
Genome Projectresponse to nitric oxide
GO:0097192
IDA
Genome Projectextrinsic apoptotic signaling pathway in absence of ligand
GO:2000425
IDA
Genome Projectregulation of apoptotic cell clearance
GO:2000536
ISS, ISO
IEA
Genome Projectnegative regulation of entry of bacterium into host cell
GO:2001237
ISO
IEA
Genome Projectnegative regulation of extrinsic apoptotic signaling pathway

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001968
ISO
IEA
Genome Projectfibronectin binding
GO:0002020
ISO
IEA
Genome Projectprotease binding
GO:0005245
ISO
IEA
Genome Projectvoltage-gated calcium channel activity
GO:0031994
ISS, ISO
IEA
Genome Projectinsulin-like growth factor I binding
GO:0046872
IEA
Genome Projectmetal ion binding
GO:0046982
TAS
Genome Projectprotein heterodimerization activity
GO:0050431
ISS
Genome Projecttransforming growth factor beta binding
GO:0050840
ISO
IEA
Genome Projectextracellular matrix binding
GO:1990430
ISO
IEA
Genome Projectextracellular matrix protein binding
GO:0001846
IDA
Genome Projectopsonin binding
GO:0005080
IDA
Genome Projectprotein kinase C binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005622
IDA
Genome Projectintracellular
GO:0005886
IDA
ISO
TAS, IEA
Genome Projectplasma membrane
GO:0005925
ISO
IEA
Genome Projectfocal adhesion
GO:0008305
ISS, ISO
IEA
Genome Projectintegrin complex
GO:0009897
IDA
Genome Projectexternal side of plasma membrane
GO:0009986
ISS, ISO
Genome Projectcell surface
GO:0016020
IDA
IEA
Genome Projectmembrane
GO:0016021
IEA
Genome Projectintegral component of membrane
GO:0031258
ISO
IEA
Genome Projectlamellipodium membrane
GO:0031527
ISO
IEA
Genome Projectfilopodium membrane
GO:0031528
ISO
IEA
Genome Projectmicrovillus membrane
GO:0032587
ISO
IEA
Genome Projectruffle membrane
GO:0034683
ISO
TAS, IEA
Genome Projectintegrin alphav-beta3 complex
GO:0034684
ISO
IEA
Genome Projectintegrin alphav-beta5 complex
GO:0034686
ISO
IEA
Genome Projectintegrin alphav-beta8 complex
GO:0035867
ISO
IEA
Genome Projectalphav-beta3 integrin-IGF-1-IGF1R complex
GO:0070062
ISO
IEA
Genome Projectextracellular exosome

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000413Integrin alpha chain
IPR013517FG-GAP repeat
IPR013519Integrin alpha beta-propellor
IPR013649Integrin alpha-2
IPR018184Integrin alpha chain, C-terminal cytoplasmic region, conserved site

No MapMan annotations defined for this gene.