Gene: ENSMUSG00000026959 (Mus musculus)

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Gene Identifier
ENSMUSG00000026959
Transcript Identifier
ENSMUST00000114310
Gene Type
Coding gene
Location
2 : 25292368-25318886 : negative

Family Information

Homologous gene family
HOM03P000932
(65 genes in 7 species)
specific family
Orthologous gene family
ORTHO03P039006
(3 genes in 3 species)
specific family

Descriptions

gene_descr
glutamate receptor, ionotropic, NMDA1 (zeta 1)

Identifiers

Type Value
UniprotA2AI21
MGI95819

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001661
IMP
Genome Projectconditioned taste aversion
GO:0001964
IMP
Genome Projectstartle response
GO:0001967
IMP
Genome Projectsuckling behavior
GO:0001975
IMP, IGI
Genome Projectresponse to amphetamine
GO:0006810
IEA
Genome Projecttransport
GO:0006811
IEA
Genome Projection transport
GO:0006812
IGI
ISO
Genome Projectcation transport
GO:0006816
IDA, IMP
Genome Projectcalcium ion transport
GO:0006874
IMP
Genome Projectcellular calcium ion homeostasis
GO:0007268
TAS
Genome Projectsynaptic transmission
GO:0007585
IMP
Genome Projectrespiratory gaseous exchange
GO:0007611
IMP
Genome Projectlearning or memory
GO:0007612
IMP
Genome Projectlearning
GO:0007613
IMP
Genome Projectmemory
GO:0007616
IMP
Genome Projectlong-term memory
GO:0008306
IMP
Genome Projectassociative learning
GO:0008344
IMP
Genome Projectadult locomotory behavior
GO:0008355
IMP
Genome Projectolfactory learning
GO:0008542
IMP, IGI
Genome Projectvisual learning
GO:0010646
IMP
Genome Projectregulation of cell communication
GO:0019233
IMP
Genome Projectsensory perception of pain
GO:0021586
IMP
Genome Projectpons maturation
GO:0021987
IMP
Genome Projectcerebral cortex development
GO:0035176
IMP
Genome Projectsocial behavior
GO:0035235
IDA
Genome Projectionotropic glutamate receptor signaling pathway
GO:0035249
IMP
Genome Projectsynaptic transmission, glutamatergic
GO:0042391
IDA, IMP
ISO
Genome Projectregulation of membrane potential
GO:0043065
IGI
Genome Projectpositive regulation of apoptotic process
GO:0043278
IMP
Genome Projectresponse to morphine
GO:0043523
IMP, IGI
Genome Projectregulation of neuron apoptotic process
GO:0043524
IMP, IGI
Genome Projectnegative regulation of neuron apoptotic process
GO:0043576
IMP
Genome Projectregulation of respiratory gaseous exchange
GO:0045471
ISO
Genome Projectresponse to ethanol
GO:0045944
IDA
Genome Projectpositive regulation of transcription from RNA polymerase II promoter
GO:0048167
IMP
Genome Projectregulation of synaptic plasticity
GO:0048168
IMP
Genome Projectregulation of neuronal synaptic plasticity
GO:0048169
IMP
Genome Projectregulation of long-term neuronal synaptic plasticity
GO:0048814
IMP
Genome Projectregulation of dendrite morphogenesis
GO:0050770
IMP
Genome Projectregulation of axonogenesis
GO:0050905
IMP
Genome Projectneuromuscular process
GO:0051963
IMP
Genome Projectregulation of synapse assembly
GO:0055074
IDA
Genome Projectcalcium ion homeostasis
GO:0060079
IMP, IGI
Genome Projectexcitatory postsynaptic potential
GO:0060134
IMP
Genome Projectprepulse inhibition
GO:0060179
IMP
Genome Projectmale mating behavior
GO:0070588
ISO
Genome Projectcalcium ion transmembrane transport

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004872
IEA
Genome Projectreceptor activity
GO:0004970
IEA
Genome Projectionotropic glutamate receptor activity
GO:0004972
IDA, IMP, IGI
ISO
Genome ProjectNMDA glutamate receptor activity
GO:0005102
IPI
Genome Projectreceptor binding
GO:0005216
IEA
Genome Projection channel activity
GO:0005234
IBA
IEA
Genome Projectextracellular-glutamate-gated ion channel activity
GO:0005261
IGI
Genome Projectcation channel activity
GO:0005262
IDA, IGI
ISO
Genome Projectcalcium channel activity
GO:0005509
IDA
Genome Projectcalcium ion binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0005516
IDA
Genome Projectcalmodulin binding
GO:0016594
ISO
Genome Projectglycine binding
GO:0016595
ISO
Genome Projectglutamate binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005737
IDA
Genome Projectcytoplasm
GO:0005783
IDA
Genome Projectendoplasmic reticulum
GO:0005886
IBA
IEA
Genome Projectplasma membrane
GO:0005887
ISO
Genome Projectintegral component of plasma membrane
GO:0008021
IDA
Genome Projectsynaptic vesicle
GO:0014069
IDA
Genome Projectpostsynaptic density
GO:0016020
IDA
IC, IEA
Genome Projectmembrane
GO:0016021
IEA
Genome Projectintegral component of membrane
GO:0017146
IPI
ISO
Genome ProjectNMDA selective glutamate receptor complex
GO:0030054
IEA
Genome Projectcell junction
GO:0030425
IDA
ISO
Genome Projectdendrite
GO:0043197
IDA
Genome Projectdendritic spine
GO:0045202
IDA
ISO
IEA
Genome Projectsynapse
GO:0045211
IDA
IEA
Genome Projectpostsynaptic membrane
GO:0097481
IDA
Genome Projectneuronal postsynaptic density

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR001320Ionotropic glutamate receptor
IPR001508Ionotropic glutamate receptor, metazoa
IPR001828Receptor, ligand binding region
IPR018882Calmodulin-binding domain C0, NMDA receptor, NR1 subunit
IPR019594Ionotropic glutamate receptor, L-glutamate and glycine-binding domain
IPR028082Periplasmic binding protein-like I

No MapMan annotations defined for this gene.