Gene: ENSMUSG00000026874 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000026874
Transcript Identifier
ENSMUST00000028233
Gene Type
Coding gene
Location
2 : 34983678-35061383 : negative

Family Information

Homologous gene family
HOM03P002669
(35 genes in 6 species)
specific family
Orthologous gene family
ORTHO03P006383
(13 genes in 2 species)
specific family

Descriptions

gene_descr
hemolytic complement

Identifiers

Type Value
UniprotP06684
MGI96031

Toolbox

Explore

Create

View

Browse

 

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001701
IGI
Genome Projectin utero embryonic development
GO:0002376
IEA
Genome Projectimmune system process
GO:0006954
IEA
Genome Projectinflammatory response
GO:0006957
IEA
Genome Projectcomplement activation, alternative pathway
GO:0006958
IEA
Genome Projectcomplement activation, classical pathway
GO:0010575
ISO
IEA
Genome Projectpositive regulation of vascular endothelial growth factor production
GO:0010760
ISO
IEA
Genome Projectnegative regulation of macrophage chemotaxis
GO:0010951
IEA
Genome Projectnegative regulation of endopeptidase activity
GO:0019835
IEA
Genome Projectcytolysis
GO:0045087
IEA
Genome Projectinnate immune response
GO:0045766
IMP
Genome Projectpositive regulation of angiogenesis
GO:0090197
ISO
IEA
Genome Projectpositive regulation of chemokine secretion
GO:0098779
ISO
Genome Projectmitophagy in response to mitochondrial depolarization
GO:1903146
IEA
Genome Projectregulation of mitophagy

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004866
IEA
Genome Projectendopeptidase inhibitor activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005576
IEA
Genome Projectextracellular region
GO:0005579
IEA
Genome Projectmembrane attack complex
GO:0005615
IEA
Genome Projectextracellular space
GO:0070062
ISO
IEA
Genome Projectextracellular exosome

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000020Anaphylatoxin/fibulin
IPR001134Netrin domain
IPR001599Alpha-2-macroglobulin
IPR002890Alpha-2-macroglobulin, N-terminal
IPR008930Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid
IPR008993Tissue inhibitor of metalloproteinases-like, OB-fold
IPR009048Alpha-macroglobulin, receptor-binding
IPR011625Alpha-2-macroglobulin, N-terminal 2
IPR011626Alpha-macroglobulin complement component
IPR018081Anaphylatoxin, complement system
IPR018933Netrin module, non-TIMP type

No MapMan annotations defined for this gene.