Gene: ENSMUSG00000026814 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000026814
Transcript Identifier
ENSMUST00000009705
Gene Type
Coding gene
Location
2 : 32646958-32681561 : positive

Family Information

Homologous gene family
HOM03P047712
(2 genes in 2 species)
specific family

Descriptions

gene_descr
endoglin

Identifiers

Type Value
UniprotQ63961
MGI95392

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000122
ISO
IEA
Genome Projectnegative regulation of transcription from RNA polymerase II promoter
GO:0001300
IEP
IEA
Genome Projectchronological cell aging
GO:0001525
IMP
IEA
Genome Projectangiogenesis
GO:0001569
IMP
Genome Projectpatterning of blood vessels
GO:0001570
IMP
ISO
IEA
Genome Projectvasculogenesis
GO:0001666
ISO
IEA
Genome Projectresponse to hypoxia
GO:0001934
ISO
IEA
Genome Projectpositive regulation of protein phosphorylation
GO:0001937
ISO
IEA
Genome Projectnegative regulation of endothelial cell proliferation
GO:0001947
IMP
Genome Projectheart looping
GO:0003084
ISO
IEA
Genome Projectpositive regulation of systemic arterial blood pressure
GO:0003273
IMP
Genome Projectcell migration involved in endocardial cushion formation
GO:0006355
ISO
IEA
Genome Projectregulation of transcription, DNA-templated
GO:0007155
IEA
Genome Projectcell adhesion
GO:0007179
IC, IEA
Genome Projecttransforming growth factor beta receptor signaling pathway
GO:0007507
IMP
Genome Projectheart development
GO:0010862
ISO
IEA
Genome Projectpositive regulation of pathway-restricted SMAD protein phosphorylation
GO:0016477
ISO
IEA
Genome Projectcell migration
GO:0017015
ISO
TAS, IEA
Genome Projectregulation of transforming growth factor beta receptor signaling pathway
GO:0022009
ISO
IEA
Genome Projectcentral nervous system vasculogenesis
GO:0022617
ISO
IEA
Genome Projectextracellular matrix disassembly
GO:0030336
ISO
IEA
Genome Projectnegative regulation of cell migration
GO:0030513
ISO
IEA
Genome Projectpositive regulation of BMP signaling pathway
GO:0031953
ISO
IEA
Genome Projectnegative regulation of protein autophosphorylation
GO:0035556
ISO
IEA
Genome Projectintracellular signal transduction
GO:0042060
ISO
IEA
Genome Projectwound healing
GO:0045766
IGI
TAS
Genome Projectpositive regulation of angiogenesis
GO:0045944
ISO
IEA
Genome Projectpositive regulation of transcription from RNA polymerase II promoter
GO:0048745
IMP
Genome Projectsmooth muscle tissue development
GO:0048844
IMP
Genome Projectartery morphogenesis
GO:0048845
IMP
Genome Projectvenous blood vessel morphogenesis
GO:0048870
ISO
IEA
Genome Projectcell motility
GO:0051001
ISO
IEA
Genome Projectnegative regulation of nitric-oxide synthase activity
GO:0060326
ISO
IEA
Genome Projectcell chemotaxis
GO:0060394
ISO
IEA
Genome Projectnegative regulation of pathway-restricted SMAD protein phosphorylation
GO:0070483
ISO
IEA
Genome Projectdetection of hypoxia

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005024
ISO
IEA
Genome Projecttransforming growth factor beta-activated receptor activity
GO:0005072
ISO
IEA
Genome Projecttransforming growth factor beta receptor, cytoplasmic mediator activity
GO:0005114
ISO
IEA
Genome Projecttype II transforming growth factor beta receptor binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0005534
ISO
IEA
Genome Projectgalactose binding
GO:0005539
ISO
IEA
Genome Projectglycosaminoglycan binding
GO:0034713
ISO
IEA
Genome Projecttype I transforming growth factor beta receptor binding
GO:0036122
ISO
IEA
Genome ProjectBMP binding
GO:0042803
IPI
ISO
IEA
Genome Projectprotein homodimerization activity
GO:0050431
IDA
ISO
IEA
Genome Projecttransforming growth factor beta binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005615
ISO
IEA
Genome Projectextracellular space
GO:0005654
ISO
IEA
Genome Projectnucleoplasm
GO:0005737
ISO
IEA
Genome Projectcytoplasm
GO:0005925
ISO
IEA
Genome Projectfocal adhesion
GO:0009897
ISO
IEA
Genome Projectexternal side of plasma membrane
GO:0009986
ISO
IEA
Genome Projectcell surface
GO:0016020
IEA
Genome Projectmembrane
GO:0016021
IEA
Genome Projectintegral component of membrane
GO:0043235
ISO
IEA
Genome Projectreceptor complex
GO:0072563
IDA
Genome Projectendothelial microparticle

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR001507Zona pellucida domain

No MapMan annotations defined for this gene.