Gene: ENSMUSG00000026778 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000026778
Transcript Identifier
ENSMUST00000028118
Gene Type
Coding gene
Location
2 : 11226868-11300125 : positive

Family Information

Homologous gene family
HOM03P000015
(1237 genes in 39 species)
specific family
Orthologous gene family
ORTHO03P005549
(15 genes in 6 species)
specific family

Descriptions

gene_descr
protein kinase C, theta

Identifiers

Type Value
UniprotQ02111
UniprotA6H667
MGI97601

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001666
IEA
Genome Projectresponse to hypoxia
GO:0006468
IDA
IEA
Genome Projectprotein phosphorylation
GO:0006954
IEA
Genome Projectinflammatory response
GO:0007568
IEA
Genome Projectaging
GO:0009408
IEA
Genome Projectresponse to heat
GO:0009749
IEA
Genome Projectresponse to glucose
GO:0010389
IEA
Genome Projectregulation of G2/M transition of mitotic cell cycle
GO:0014070
IEA
Genome Projectresponse to organic cyclic compound
GO:0016310
IEA
Genome Projectphosphorylation
GO:0019229
IEA
Genome Projectregulation of vasoconstriction
GO:0030182
IEA
Genome Projectneuron differentiation
GO:0032868
IEA
Genome Projectresponse to insulin
GO:0035556
IMP
IEA
Genome Projectintracellular signal transduction
GO:0042102
IMP
Genome Projectpositive regulation of T cell proliferation
GO:0042246
IEA
Genome Projecttissue regeneration
GO:0042346
IEA
Genome Projectpositive regulation of NF-kappaB import into nucleus
GO:0045086
IMP
Genome Projectpositive regulation of interleukin-2 biosynthetic process
GO:0045730
IEA
Genome Projectrespiratory burst
GO:0046627
ISS, ISO
IEA
Genome Projectnegative regulation of insulin receptor signaling pathway
GO:0050714
IEA
Genome Projectpositive regulation of protein secretion
GO:0050870
IMP
Genome Projectpositive regulation of T cell activation
GO:0051092
IMP
ISO
IEA
Genome Projectpositive regulation of NF-kappaB transcription factor activity
GO:0051491
IEA
Genome Projectpositive regulation of filopodium assembly
GO:0051496
IEA
Genome Projectpositive regulation of stress fiber assembly
GO:0070233
ISS, ISO
IEA
Genome Projectnegative regulation of T cell apoptotic process
GO:0002376
IEA
Genome Projectimmune system process
GO:0006355
IMP
Genome Projectregulation of transcription, DNA-templated
GO:0006509
IDA
Genome Projectmembrane protein ectodomain proteolysis
GO:0032740
IMP
Genome Projectpositive regulation of interleukin-17 production
GO:0032753
IMP
Genome Projectpositive regulation of interleukin-4 production
GO:0090330
IMP
Genome Projectregulation of platelet aggregation
GO:2000318
IMP
Genome Projectpositive regulation of T-helper 17 type immune response
GO:2000570
IMP
Genome Projectpositive regulation of T-helper 2 cell activation

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000166
IEA
Genome Projectnucleotide binding
GO:0004672
IEA
Genome Projectprotein kinase activity
GO:0004674
IEA
Genome Projectprotein serine/threonine kinase activity
GO:0004697
IDA
IEA
Genome Projectprotein kinase C activity
GO:0005524
IEA
Genome ProjectATP binding
GO:0016301
IEA
Genome Projectkinase activity
GO:0016740
IEA
Genome Projecttransferase activity
GO:0046872
IEA
Genome Projectmetal ion binding
GO:0005515
IPI
Genome Projectprotein binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001772
IDA
Genome Projectimmunological synapse
GO:0005634
IEA
Genome Projectnucleus
GO:0005737
IDA
IEA
Genome Projectcytoplasm
GO:0005886
IDA
IEA
Genome Projectplasma membrane
GO:0016020
IEA
Genome Projectmembrane
GO:0031594
IEA
Genome Projectneuromuscular junction
GO:0042383
IEA
Genome Projectsarcolemma

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000008C2 domain
IPR000719Protein kinase domain
IPR000961AGC-kinase, C-terminal
IPR002219Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
IPR002290Serine/threonine/dual specificity protein kinase, catalytic domain
IPR008271Serine/threonine-protein kinase, active site
IPR011009Protein kinase-like domain
IPR014376Protein kinase C, delta/epsilon/eta/theta types
IPR017441Protein kinase, ATP binding site
IPR017892Protein kinase, C-terminal
IPR020454Diacylglycerol/phorbol-ester binding
IPR027264Protein kinase C, theta

No MapMan annotations defined for this gene.