Gene: ENSMUSG00000026770 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000026770
Transcript Identifier
ENSMUST00000028111
Gene Type
Coding gene
Location
2 : 11643001-11689782 : positive

Family Information

Homologous gene family
HOM03P045461
(2 genes in 2 species)
specific family

Descriptions

gene_descr
interleukin 2 receptor, alpha chain

Identifiers

Type Value
UniprotP01590
UniprotQ544I2
MGI96549

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0002437
IEA
Genome Projectinflammatory response to antigenic stimulus
GO:0006924
IMP
Genome Projectactivation-induced cell death of T cells
GO:0006954
IBA
Genome Projectinflammatory response
GO:0006955
IBA
Genome Projectimmune response
GO:0007219
IGI
Genome ProjectNotch signaling pathway
GO:0038110
IMP
IEA
Genome Projectinterleukin-2-mediated signaling pathway
GO:0042102
IEA
Genome Projectpositive regulation of T cell proliferation
GO:0042104
IMP
Genome Projectpositive regulation of activated T cell proliferation
GO:0042130
IMP
Genome Projectnegative regulation of T cell proliferation
GO:0043029
IMP
Genome ProjectT cell homeostasis
GO:0045582
IEA
Genome Projectpositive regulation of T cell differentiation
GO:0046013
IMP
Genome Projectregulation of T cell homeostatic proliferation
GO:0050672
IMP
Genome Projectnegative regulation of lymphocyte proliferation
GO:0050687
IEA
Genome Projectnegative regulation of defense response to virus
GO:0050728
IMP
Genome Projectnegative regulation of inflammatory response
GO:0050777
IEA
Genome Projectnegative regulation of immune response

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004911
IMP
IEA
Genome Projectinterleukin-2 receptor activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0008144
IEA
Genome Projectdrug binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0009897
IDA
Genome Projectexternal side of plasma membrane
GO:0009986
IEA
Genome Projectcell surface
GO:0016020
IEA
Genome Projectmembrane
GO:0016021
IEA
Genome Projectintegral component of membrane

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000436Sushi/SCR/CCP domain
IPR015486Interleukin-2 receptor alpha

No MapMan annotations defined for this gene.