Gene: ENSMUSG00000026672 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000026672
Transcript Identifier
ENSMUST00000027986
Gene Type
Coding gene
Location
2 : 5021351-5054705 : negative

Family Information

Homologous gene family
HOM03P028344
(3 genes in 2 species)
specific family

Descriptions

gene_descr
optineurin

Identifiers

Type Value
UniprotQ8K3K8
MGI1918898

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000042
ISO, IBA
IEA
Genome Projectprotein targeting to Golgi
GO:0001920
ISO
IEA
Genome Projectnegative regulation of receptor recycling
GO:0006914
IEA
Genome Projectautophagy
GO:0007030
ISO
IEA
Genome ProjectGolgi organization
GO:0008284
IEA
Genome Projectpositive regulation of cell proliferation
GO:0016236
ISO
IEA
Genome Projectmacroautophagy
GO:0034613
IMP
Genome Projectcellular protein localization
GO:0042060
IEA
Genome Projectwound healing
GO:0043001
ISO
IEA
Genome ProjectGolgi to plasma membrane protein transport
GO:0043124
IMP
Genome Projectnegative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043524
IEA
Genome Projectnegative regulation of neuron apoptotic process
GO:0050663
IEA
Genome Projectcytokine secretion
GO:0050829
ISO
IEA
Genome Projectdefense response to Gram-negative bacterium
GO:0051260
IEA
Genome Projectprotein homooligomerization
GO:0090161
ISS, ISO, IBA
IEA
Genome ProjectGolgi ribbon formation

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001155
IEA
Genome ProjectTFIIIA-class transcription factor binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0008022
ISO
IEA
Genome Projectprotein C-terminus binding
GO:0017137
ISO
IEA
Genome ProjectRab GTPase binding
GO:0031593
ISO
IEA
Genome Projectpolyubiquitin binding
GO:0042802
ISO
IEA
Genome Projectidentical protein binding
GO:0043130
IEA
Genome Projectubiquitin binding
GO:0070530
IDA
Genome ProjectK63-linked polyubiquitin binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IBA
Genome Projectnucleus
GO:0005737
ISO, IBA
IEA
Genome Projectcytoplasm
GO:0005768
IEA
Genome Projectendosome
GO:0005776
IEA
Genome Projectautophagosome
GO:0005794
ISO, IBA
IEA
Genome ProjectGolgi apparatus
GO:0005802
ISS, ISO
IEA
Genome Projecttrans-Golgi network
GO:0016023
IBA
IEA
Genome Projectcytoplasmic membrane-bounded vesicle
GO:0031410
IEA
Genome Projectcytoplasmic vesicle
GO:0048471
IDA
IEA
Genome Projectperinuclear region of cytoplasm
GO:0055037
IEA
Genome Projectrecycling endosome

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR021063NF-kappa-B essential modulator NEMO, N-terminal
IPR032419NF-kappa-B essential modulator NEMO, CC2-LZ domain

No MapMan annotations defined for this gene.