Gene: ENSMUSG00000026596 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000026596
Transcript Identifier
ENSMUST00000027888
Gene Type
Coding gene
Location
1 : 156559049-156642716 : positive

Family Information

Homologous gene family
HOM03P000004
(1817 genes in 37 species)
specific family
Orthologous gene family
ORTHO03P035233
(3 genes in 2 species)
specific family

Descriptions

gene_descr
v-abl Abelson murine leukemia viral oncogene 2 (arg, Abelson-related gene)

Identifiers

Type Value
UniprotF8VQH0
MGI87860

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006468
IEA
Genome Projectprotein phosphorylation
GO:0006909
IMP, IGI
Genome Projectphagocytosis
GO:0006930
IGI
Genome Projectsubstrate-dependent cell migration, cell extension
GO:0007015
IDA
Genome Projectactin filament organization
GO:0007173
IGI
Genome Projectepidermal growth factor receptor signaling pathway
GO:0007204
ISO
IEA
Genome Projectpositive regulation of cytosolic calcium ion concentration
GO:0007612
IMP
Genome Projectlearning
GO:0008542
IGI
Genome Projectvisual learning
GO:0010863
ISO
IEA
Genome Projectpositive regulation of phospholipase C activity
GO:0010976
IGI
ISO
IEA
Genome Projectpositive regulation of neuron projection development
GO:0016310
IEA
Genome Projectphosphorylation
GO:0016322
IMP
Genome Projectneuron remodeling
GO:0016477
IBA
Genome Projectcell migration
GO:0018108
ISO
IEA
Genome Projectpeptidyl-tyrosine phosphorylation
GO:0021587
IGI
Genome Projectcerebellum morphogenesis
GO:0022408
IGI
Genome Projectnegative regulation of cell-cell adhesion
GO:0032092
IMP
Genome Projectpositive regulation of protein binding
GO:0034613
IMP
Genome Projectcellular protein localization
GO:0035024
IGI
Genome Projectnegative regulation of Rho protein signal transduction
GO:0035640
IGI
Genome Projectexploration behavior
GO:0038083
IBA
Genome Projectpeptidyl-tyrosine autophosphorylation
GO:0042127
IBA
Genome Projectregulation of cell proliferation
GO:0043123
IGI
Genome Projectpositive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0045087
IBA
Genome Projectinnate immune response
GO:0046632
IGI
Genome Projectalpha-beta T cell differentiation
GO:0048008
IGI
Genome Projectplatelet-derived growth factor receptor signaling pathway
GO:0048813
IMP, IGI
Genome Projectdendrite morphogenesis
GO:0050885
IGI
Genome Projectneuromuscular process controlling balance
GO:0051017
IDA
Genome Projectactin filament bundle assembly
GO:0051353
ISO
IEA
Genome Projectpositive regulation of oxidoreductase activity
GO:0060020
IGI
Genome ProjectBergmann glial cell differentiation
GO:0070374
IGI
Genome Projectpositive regulation of ERK1 and ERK2 cascade
GO:0071300
ISO
IEA
Genome Projectcellular response to retinoic acid
GO:0097062
IMP, IGI
Genome Projectdendritic spine maintenance
GO:1900042
IGI
Genome Projectpositive regulation of interleukin-2 secretion
GO:1902715
IGI
Genome Projectpositive regulation of interferon-gamma secretion
GO:1903053
IGI
Genome Projectregulation of extracellular matrix organization
GO:2000096
IGI
Genome Projectpositive regulation of Wnt signaling pathway, planar cell polarity pathway
GO:2000352
IGI
Genome Projectnegative regulation of endothelial cell apoptotic process

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000166
IEA
Genome Projectnucleotide binding
GO:0000287
ISO
IEA
Genome Projectmagnesium ion binding
GO:0004672
IEA
Genome Projectprotein kinase activity
GO:0004713
IDA, IMP, IGI
ISO
IEA
Genome Projectprotein tyrosine kinase activity
GO:0004715
IBA
IEA
Genome Projectnon-membrane spanning protein tyrosine kinase activity
GO:0005102
IBA
Genome Projectreceptor binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0005524
IEA
Genome ProjectATP binding
GO:0016301
IEA
Genome Projectkinase activity
GO:0016740
IEA
Genome Projecttransferase activity
GO:0030145
ISO
IEA
Genome Projectmanganese ion binding
GO:0046872
IEA
Genome Projectmetal ion binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001891
IDA
Genome Projectphagocytic cup
GO:0005829
ISO
IEA
Genome Projectcytosol
GO:0015629
IDA
Genome Projectactin cytoskeleton
GO:0016023
TAS
Genome Projectcytoplasmic membrane-bounded vesicle
GO:0030027
IDA
Genome Projectlamellipodium
GO:0031234
IBA
Genome Projectextrinsic component of cytoplasmic side of plasma membrane
GO:0043197
IDA
Genome Projectdendritic spine

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000719Protein kinase domain
IPR000980SH2 domain
IPR001245Serine-threonine/tyrosine-protein kinase catalytic domain
IPR001452SH3 domain
IPR008266Tyrosine-protein kinase, active site
IPR011009Protein kinase-like domain
IPR015015F-actin binding
IPR017441Protein kinase, ATP binding site
IPR020635Tyrosine-protein kinase, catalytic domain

No MapMan annotations defined for this gene.