Gene: ENSMUSG00000026509 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000026509
Transcript Identifier
ENSMUST00000068505
Gene Type
Coding gene
Location
1 : 182468212-182517354 : negative

Family Information

Homologous gene family
HOM03P000288
(137 genes in 25 species)
specific family
Orthologous gene family
ORTHO03P003966
(21 genes in 8 species)
specific family
Duplication type
Tandem duplicate

Descriptions

gene_descr
calpain 2

Identifiers

Type Value
UniprotO08529
MGI88264

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001666
IEA
Genome Projectresponse to hypoxia
GO:0001824
IMP
Genome Projectblastocyst development
GO:0006508
IDA
IEA
Genome Projectproteolysis
GO:0007520
IMP
Genome Projectmyoblast fusion
GO:0016540
IEA
Genome Projectprotein autoprocessing
GO:0051493
IEA
Genome Projectregulation of cytoskeleton organization
GO:0071230
IDA
IEA
Genome Projectcellular response to amino acid stimulus

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004198
IDA
TAS, IEA
Genome Projectcalcium-dependent cysteine-type endopeptidase activity
GO:0005509
IEA
Genome Projectcalcium ion binding
GO:0008092
IEA
Genome Projectcytoskeletal protein binding
GO:0008233
IDA
IEA
Genome Projectpeptidase activity
GO:0008234
IEA
Genome Projectcysteine-type peptidase activity
GO:0016787
IEA
Genome Projecthydrolase activity
GO:0046872
IEA
Genome Projectmetal ion binding
GO:0046982
IEA
Genome Projectprotein heterodimerization activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000785
IDA
Genome Projectchromatin
GO:0005622
IEA
Genome Projectintracellular
GO:0005634
IDA
Genome Projectnucleus
GO:0005737
IDA
ISO
IEA
Genome Projectcytoplasm
GO:0005764
IDA
Genome Projectlysosome
GO:0005783
ISO
IEA
Genome Projectendoplasmic reticulum
GO:0005794
ISO
IEA
Genome ProjectGolgi apparatus
GO:0005829
IDA
ISS, ISO
IEA
Genome Projectcytosol
GO:0005886
ISS, ISO
IEA
Genome Projectplasma membrane
GO:0005925
ISO
IEA
Genome Projectfocal adhesion
GO:0016020
IEA
Genome Projectmembrane
GO:0030425
IEA
Genome Projectdendrite
GO:0031143
ISO
IEA
Genome Projectpseudopodium
GO:0045121
ISS, ISO
IEA
Genome Projectmembrane raft
GO:0070062
ISO
IEA
Genome Projectextracellular exosome
GO:0097038
ISO
IEA
Genome Projectperinuclear endoplasmic reticulum

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000169Cysteine peptidase, cysteine active site
IPR001300Peptidase C2, calpain, catalytic domain
IPR002048EF-hand domain
IPR011992EF-hand domain pair
IPR018247EF-Hand 1, calcium-binding site
IPR022682Peptidase C2, calpain, large subunit, domain III
IPR022683Peptidase C2, calpain, domain III
IPR022684Peptidase C2, calpain family
IPR029539Calpain-2

No MapMan annotations defined for this gene.