Gene: ENSMUSG00000026473 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000026473
Transcript Identifier
ENSMUST00000086199
Gene Type
Coding gene
Location
1 : 153902947-153908182 : positive

Family Information

Homologous gene family
HOM03P000633
(83 genes in 31 species)
specific family
Orthologous gene family
ORTHO03P000204
(62 genes in 31 species)
specific family

Descriptions

gene_descr
glutamate-ammonia ligase (glutamine synthetase)

Identifiers

Type Value
UniprotP15105
MGI95739

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006536
IEA
Genome Projectglutamate metabolic process
GO:0006542
IEA
Genome Projectglutamine biosynthetic process
GO:0006807
IEA
Genome Projectnitrogen compound metabolic process
GO:0008283
ISO
IEA
Genome Projectcell proliferation
GO:0009267
IEP
Genome Projectcellular response to starvation
GO:0009749
IMP
Genome Projectresponse to glucose
GO:0032024
IEA
Genome Projectpositive regulation of insulin secretion
GO:0050679
IEA
Genome Projectpositive regulation of epithelial cell proliferation
GO:0051260
IEA
Genome Projectprotein homooligomerization
GO:0051968
IEA
Genome Projectpositive regulation of synaptic transmission, glutamatergic

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000166
IEA
Genome Projectnucleotide binding
GO:0000287
IEA
Genome Projectmagnesium ion binding
GO:0003824
IEA
Genome Projectcatalytic activity
GO:0004351
IEA
Genome Projectglutamate decarboxylase activity
GO:0004356
ISO
IEA
Genome Projectglutamate-ammonia ligase activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0005524
IEA
Genome ProjectATP binding
GO:0016595
IEA
Genome Projectglutamate binding
GO:0016829
IEA
Genome Projectlyase activity
GO:0016874
IEA
Genome Projectligase activity
GO:0030145
IEA
Genome Projectmanganese ion binding
GO:0042802
ISO
IEA
Genome Projectidentical protein binding
GO:0045503
IEA
Genome Projectdynein light chain binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
ISO
IEA
Genome Projectnucleus
GO:0005737
IDA
ISO
IEA
Genome Projectcytoplasm
GO:0005739
IDA
IEA
Genome Projectmitochondrion
GO:0005791
IEA
Genome Projectrough endoplasmic reticulum
GO:0042995
IEA
Genome Projectcell projection
GO:0043005
IEA
Genome Projectneuron projection
GO:0043204
IEA
Genome Projectperikaryon
GO:0043209
IDA
IEA
Genome Projectmyelin sheath
GO:0043231
IEA
Genome Projectintracellular membrane-bounded organelle
GO:0043234
IEA
Genome Projectprotein complex
GO:0043679
IEA
Genome Projectaxon terminus
GO:0044297
IDA
Genome Projectcell body
GO:0070062
ISO
IEA
Genome Projectextracellular exosome
GO:0097386
IDA
Genome Projectglial cell projection

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR008146Glutamine synthetase, catalytic domain
IPR008147Glutamine synthetase, beta-Grasp domain
IPR014746Glutamine synthetase/guanido kinase, catalytic domain
IPR027302Glutamine synthetase, N-terminal conserved site
IPR027303Glutamine synthetase, glycine-rich site

No MapMan annotations defined for this gene.