Gene: ENSMUSG00000026313 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000026313
Transcript Identifier
ENSMUST00000008995
Gene Type
Coding gene
Location
1 : 91933347-92148277 : negative

Family Information

Homologous gene family
HOM03P000083
(314 genes in 39 species)
specific family
Orthologous gene family
ORTHO03P012093
(7 genes in 2 species)
specific family

Descriptions

gene_descr
histone deacetylase 4

Identifiers

Type Value
UniprotQ6NZM9
MGI3036234

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000122
IDA, IGI
ISO
IEA
Genome Projectnegative regulation of transcription from RNA polymerase II promoter
GO:0001501
IMP
Genome Projectskeletal system development
GO:0002076
IMP
Genome Projectosteoblast development
GO:0006338
ISO
IEA
Genome Projectchromatin remodeling
GO:0006351
IEA
Genome Projecttranscription, DNA-templated
GO:0006355
IEA
Genome Projectregulation of transcription, DNA-templated
GO:0008284
ISO
IEA
Genome Projectpositive regulation of cell proliferation
GO:0008285
IDA, IMP
Genome Projectnegative regulation of cell proliferation
GO:0010592
IEA
Genome Projectpositive regulation of lamellipodium assembly
GO:0010832
ISO
IEA
Genome Projectnegative regulation of myotube differentiation
GO:0010882
IMP
Genome Projectregulation of cardiac muscle contraction by calcium ion signaling
GO:0014894
IMP
Genome Projectresponse to denervation involved in regulation of muscle adaptation
GO:0014911
IEA
Genome Projectpositive regulation of smooth muscle cell migration
GO:0016568
IEA
Genome Projectchromatin modification
GO:0016575
ISO
IEA
Genome Projecthistone deacetylation
GO:0033235
ISS, ISO
IEA
Genome Projectpositive regulation of protein sumoylation
GO:0034983
ISO
IEA
Genome Projectpeptidyl-lysine deacetylation
GO:0040029
ISO
IEA
Genome Projectregulation of gene expression, epigenetic
GO:0042493
IEA
Genome Projectresponse to drug
GO:0043393
ISO
IEA
Genome Projectregulation of protein binding
GO:0043433
ISO
IEA
Genome Projectnegative regulation of sequence-specific DNA binding transcription factor activity
GO:0043525
IEA
Genome Projectpositive regulation of neuron apoptotic process
GO:0045668
IMP
Genome Projectnegative regulation of osteoblast differentiation
GO:0045820
IMP
Genome Projectnegative regulation of glycolytic process
GO:0045892
IDA, IMP
ISO
IEA
Genome Projectnegative regulation of transcription, DNA-templated
GO:0045893
IMP
Genome Projectpositive regulation of transcription, DNA-templated
GO:0045944
IMP
ISO
Genome Projectpositive regulation of transcription from RNA polymerase II promoter
GO:0048661
IEA
Genome Projectpositive regulation of smooth muscle cell proliferation
GO:0048742
IGI
Genome Projectregulation of skeletal muscle fiber development
GO:0051091
ISO
IEA
Genome Projectpositive regulation of sequence-specific DNA binding transcription factor activity
GO:0051153
IGI
Genome Projectregulation of striated muscle cell differentiation
GO:0070555
ISO
IEA
Genome Projectresponse to interleukin-1
GO:0070932
ISO
IEA
Genome Projecthistone H3 deacetylation
GO:0070933
ISO
IEA
Genome Projecthistone H4 deacetylation
GO:0071260
IEA
Genome Projectcellular response to mechanical stimulus
GO:0071356
IEA
Genome Projectcellular response to tumor necrosis factor
GO:0071374
IEA
Genome Projectcellular response to parathyroid hormone stimulus
GO:1903428
IEA
Genome Projectpositive regulation of reactive oxygen species biosynthetic process

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001025
ISO
IEA
Genome ProjectRNA polymerase III transcription factor binding
GO:0001047
ISO
IEA
Genome Projectcore promoter binding
GO:0003677
IDA
Genome ProjectDNA binding
GO:0003682
IDA
Genome Projectchromatin binding
GO:0003714
IGI
Genome Projecttranscription corepressor activity
GO:0004407
ISO
IEA
Genome Projecthistone deacetylase activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0008134
IPI
ISO
IEA
Genome Projecttranscription factor binding
GO:0008270
ISO
IEA
Genome Projectzinc ion binding
GO:0016787
IEA
Genome Projecthydrolase activity
GO:0019901
IPI
Genome Projectprotein kinase binding
GO:0030955
ISO
IEA
Genome Projectpotassium ion binding
GO:0032041
IEA
Genome ProjectNAD-dependent histone deacetylase activity (H3-K14 specific)
GO:0033558
IDA
ISO
IEA
Genome Projectprotein deacetylase activity
GO:0033613
ISO
IEA
Genome Projectactivating transcription factor binding
GO:0042826
ISO
IEA
Genome Projecthistone deacetylase binding
GO:0043565
ISO
IEA
Genome Projectsequence-specific DNA binding
GO:0044212
ISO
IEA
Genome Projecttranscription regulatory region DNA binding
GO:0046872
IEA
Genome Projectmetal ion binding
GO:0070491
ISO
IEA
Genome Projectrepressing transcription factor binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000118
ISO
IEA
Genome Projecthistone deacetylase complex
GO:0005634
IDA, IMP
ISO
IEA
Genome Projectnucleus
GO:0005654
ISO
IEA
Genome Projectnucleoplasm
GO:0005737
IDA, IMP
ISO
IEA
Genome Projectcytoplasm
GO:0005829
IDA
IEA
Genome Projectcytosol
GO:0017053
ISO
IEA
Genome Projecttranscriptional repressor complex
GO:0030017
ISO
IEA
Genome Projectsarcomere
GO:0030018
ISO
IEA
Genome ProjectZ disc
GO:0031594
IDA
Genome Projectneuromuscular junction
GO:0031672
ISO
IEA
Genome ProjectA band
GO:0042641
IDA
Genome Projectactomyosin
GO:0043234
IEA
Genome Projectprotein complex

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000286Histone deacetylase superfamily
IPR017320Histone deacetylase class II, eukaryotic
IPR023801Histone deacetylase domain
IPR024643Histone deacetylase, glutamine rich N-terminal domain

No MapMan annotations defined for this gene.