Gene: ENSMUSG00000026249 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000026249
Transcript Identifier
ENSMUST00000027467
Gene Type
Coding gene
Location
1 : 79795005-79821535 : negative

Family Information

Homologous gene family
HOM03P000183
(176 genes in 15 species)
specific family
Orthologous gene family
ORTHO03P066573
(2 genes in 2 species)
specific family
Duplication type
Block duplicate

Descriptions

gene_descr
serine (or cysteine) peptidase inhibitor, clade E, member 2

Identifiers

Type Value
UniprotQ07235
UniprotQ543R5
MGI101780

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0007275
IEA
Genome Projectmulticellular organismal development
GO:0007399
IEA
Genome Projectnervous system development
GO:0007566
IEA
Genome Projectembryo implantation
GO:0007596
IMP
Genome Projectblood coagulation
GO:0008285
IGI
Genome Projectnegative regulation of cell proliferation
GO:0009314
IEA
Genome Projectresponse to radiation
GO:0009611
IMP
Genome Projectresponse to wounding
GO:0010466
IMP
IEA
Genome Projectnegative regulation of peptidase activity
GO:0010544
IMP
Genome Projectnegative regulation of platelet activation
GO:0010757
IMP
ISO
IEA
Genome Projectnegative regulation of plasminogen activation
GO:0010766
IMP, IGI
Genome Projectnegative regulation of sodium ion transport
GO:0010951
IMP
ISO
IEA
Genome Projectnegative regulation of endopeptidase activity
GO:0010955
IC
Genome Projectnegative regulation of protein processing
GO:0010976
IEA
Genome Projectpositive regulation of neuron projection development
GO:0014067
IGI
Genome Projectnegative regulation of phosphatidylinositol 3-kinase signaling
GO:0021683
IMP
Genome Projectcerebellar granular layer morphogenesis
GO:0030154
IEA
Genome Projectcell differentiation
GO:0030195
ISO
IEA
Genome Projectnegative regulation of blood coagulation
GO:0030308
IGI
Genome Projectnegative regulation of cell growth
GO:0032940
IMP
ISO
Genome Projectsecretion by cell
GO:0033363
IMP
ISO
IEA
Genome Projectsecretory granule organization
GO:0042177
IMP
ISO
Genome Projectnegative regulation of protein catabolic process
GO:0042628
IMP
Genome Projectmating plug formation
GO:0045861
ISO
IEA
Genome Projectnegative regulation of proteolysis
GO:0045879
IGI
Genome Projectnegative regulation of smoothened signaling pathway
GO:0048505
IMP
Genome Projectregulation of timing of cell differentiation
GO:0048711
ISO
IEA
Genome Projectpositive regulation of astrocyte differentiation
GO:0050974
IMP
Genome Projectdetection of mechanical stimulus involved in sensory perception
GO:0051966
IMP
Genome Projectregulation of synaptic transmission, glutamatergic
GO:0060291
IMP
Genome Projectlong-term synaptic potentiation
GO:0060384
IMP
Genome Projectinnervation
GO:0061108
IMP
Genome Projectseminal vesicle epithelium development
GO:0061110
IEA
Genome Projectdense core granule biogenesis
GO:0090331
IMP
Genome Projectnegative regulation of platelet aggregation

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004867
IMP
ISO
IEA
Genome Projectserine-type endopeptidase inhibitor activity
GO:0005102
IGI
ISO
IEA
Genome Projectreceptor binding
GO:0005539
ISO
IEA
Genome Projectglycosaminoglycan binding
GO:0008201
ISO
IEA
Genome Projectheparin binding
GO:0030414
IEA
Genome Projectpeptidase inhibitor activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005576
IDA
ISO
IEA
Genome Projectextracellular region
GO:0005615
IBA
IEA
Genome Projectextracellular space
GO:0005829
ISO
IEA
Genome Projectcytosol
GO:0016020
IEA
Genome Projectmembrane
GO:0031012
ISO
IEA
Genome Projectextracellular matrix
GO:0031091
ISO
IEA
Genome Projectplatelet alpha granule
GO:0031232
ISO
IEA
Genome Projectextrinsic component of external side of plasma membrane
GO:0031594
IDA
Genome Projectneuromuscular junction
GO:0031982
IEA
Genome Projectvesicle
GO:0043025
IEA
Genome Projectneuronal cell body
GO:1903561
ISO
Genome Projectextracellular vesicle

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000215Serpin family
IPR023795Serpin, conserved site
IPR023796Serpin domain

No MapMan annotations defined for this gene.