Gene: ENSMUSG00000026180 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000026180
Transcript Identifier
ENSMUST00000106899
Gene Type
Coding gene
Location
1 : 74158349-74159428 : positive

Family Information

Homologous gene family
HOM03P000080
(330 genes in 4 species)
specific family
Orthologous gene family
ORTHO03P073927
(2 genes in 2 species)
specific family
Duplication type
Tandem duplicate

Descriptions

gene_descr
chemokine (C-X-C motif) receptor 2

Identifiers

Type Value
UniprotP35343
MGI105303

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0002438
IEA
Genome Projectacute inflammatory response to antigenic stimulus
GO:0002690
IEA
Genome Projectpositive regulation of leukocyte chemotaxis
GO:0006935
ISO
TAS, IEA
Genome Projectchemotaxis
GO:0006968
ISO
Genome Projectcellular defense response
GO:0007165
ISO
IEA
Genome Projectsignal transduction
GO:0007166
ISO
Genome Projectcell surface receptor signaling pathway
GO:0007186
IEA
Genome ProjectG-protein coupled receptor signaling pathway
GO:0007200
ISO
Genome Projectphospholipase C-activating G-protein coupled receptor signaling pathway
GO:0007204
IEA
Genome Projectpositive regulation of cytosolic calcium ion concentration
GO:0008284
ISO
Genome Projectpositive regulation of cell proliferation
GO:0010666
IEA
Genome Projectpositive regulation of cardiac muscle cell apoptotic process
GO:0030593
ISO
IEA
Genome Projectneutrophil chemotaxis
GO:0030901
IEA
Genome Projectmidbrain development
GO:0031623
ISO
Genome Projectreceptor internalization
GO:0033030
IEA
Genome Projectnegative regulation of neutrophil apoptotic process
GO:0038112
ISO
Genome Projectinterleukin-8-mediated signaling pathway
GO:0042119
ISO
Genome Projectneutrophil activation
GO:0043066
IMP
IEA
Genome Projectnegative regulation of apoptotic process
GO:0043117
IEA
Genome Projectpositive regulation of vascular permeability
GO:0045766
IEA
Genome Projectpositive regulation of angiogenesis
GO:0070098
ISO
Genome Projectchemokine-mediated signaling pathway
GO:0072173
IEA
Genome Projectmetanephric tubule morphogenesis
GO:0090023
IEA
Genome Projectpositive regulation of neutrophil chemotaxis

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004871
ISO
IEA
Genome Projectsignal transducer activity
GO:0004918
ISO
TAS
Genome Projectinterleukin-8 receptor activity
GO:0004930
IEA
Genome ProjectG-protein coupled receptor activity
GO:0004950
IDA
TAS, IEA
Genome Projectchemokine receptor activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0016494
ISO
IEA
Genome ProjectC-X-C chemokine receptor activity
GO:0019959
ISO
IEA
Genome Projectinterleukin-8 binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005622
ISO
Genome Projectintracellular
GO:0005829
IEA
Genome Projectcytosol
GO:0005886
IEA
Genome Projectplasma membrane
GO:0009986
ISO
Genome Projectcell surface
GO:0016020
ISO
IEA
Genome Projectmembrane
GO:0016021
IEA
Genome Projectintegral component of membrane
GO:0042629
ISO
Genome Projectmast cell granule

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000057CXC chemokine receptor 2
IPR000174CXC chemokine receptor 1/2
IPR000276G protein-coupled receptor, rhodopsin-like
IPR017452GPCR, rhodopsin-like, 7TM

No MapMan annotations defined for this gene.