Gene: ENSMUSG00000026117 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000026117
Transcript Identifier
ENSMUST00000027291
Gene Type
Coding gene
Location
1 : 36770811-36782584 : positive

Family Information

Homologous gene family
HOM03P000004
(1817 genes in 37 species)
specific family
Orthologous gene family
ORTHO03P031657
(3 genes in 2 species)
specific family

Descriptions

gene_descr
zeta-chain (TCR) associated protein kinase

Identifiers

Type Value
UniprotP43404
MGI99613

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0002250
IEA
Genome Projectadaptive immune response
GO:0002376
IEA
Genome Projectimmune system process
GO:0006468
IDA
ISO
IEA
Genome Projectprotein phosphorylation
GO:0006955
ISO
IEA
Genome Projectimmune response
GO:0007169
IBA
Genome Projecttransmembrane receptor protein tyrosine kinase signaling pathway
GO:0016310
IEA
Genome Projectphosphorylation
GO:0016477
IBA
Genome Projectcell migration
GO:0018108
IDA, IMP
ISO
IEA
Genome Projectpeptidyl-tyrosine phosphorylation
GO:0030154
IBA
Genome Projectcell differentiation
GO:0035556
IMP
IEA
Genome Projectintracellular signal transduction
GO:0038083
IBA
Genome Projectpeptidyl-tyrosine autophosphorylation
GO:0043366
IGI
Genome Projectbeta selection
GO:0045059
IMP
ISO
IEA
Genome Projectpositive thymic T cell selection
GO:0045060
IMP
Genome Projectnegative thymic T cell selection
GO:0045061
IMP
Genome Projectthymic T cell selection
GO:0045087
IBA
Genome Projectinnate immune response
GO:0045582
IMP
ISO
IEA
Genome Projectpositive regulation of T cell differentiation
GO:0046638
IMP, IGI
Genome Projectpositive regulation of alpha-beta T cell differentiation
GO:0046641
IGI
Genome Projectpositive regulation of alpha-beta T cell proliferation
GO:0046777
IDA, IMP
Genome Projectprotein autophosphorylation
GO:0050850
IMP
Genome Projectpositive regulation of calcium-mediated signaling
GO:0050852
IMP
Genome ProjectT cell receptor signaling pathway

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000166
IEA
Genome Projectnucleotide binding
GO:0001784
IPI
Genome Projectphosphotyrosine binding
GO:0004672
IDA
IEA
Genome Projectprotein kinase activity
GO:0004713
IDA, IMP
ISO
IEA
Genome Projectprotein tyrosine kinase activity
GO:0004715
IBA
IEA
Genome Projectnon-membrane spanning protein tyrosine kinase activity
GO:0005102
IBA
Genome Projectreceptor binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0005524
IDA
IEA
Genome ProjectATP binding
GO:0016301
IEA
Genome Projectkinase activity
GO:0016740
IEA
Genome Projecttransferase activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001772
IDA
Genome Projectimmunological synapse
GO:0005737
IDA
IEA
Genome Projectcytoplasm
GO:0005829
IDA
Genome Projectcytosol
GO:0005886
IDA
ISO
IEA
Genome Projectplasma membrane
GO:0005911
IDA
Genome Projectcell-cell junction
GO:0016020
IEA
Genome Projectmembrane
GO:0031234
IBA
Genome Projectextrinsic component of cytoplasmic side of plasma membrane
GO:0042101
ISO
IEA
Genome ProjectT cell receptor complex
GO:0045121
ISO
IEA
Genome Projectmembrane raft

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000719Protein kinase domain
IPR000980SH2 domain
IPR001245Serine-threonine/tyrosine-protein kinase catalytic domain
IPR008266Tyrosine-protein kinase, active site
IPR011009Protein kinase-like domain
IPR012234Tyrosine-protein kinase, non-receptor SYK/ZAP-70
IPR017441Protein kinase, ATP binding site
IPR020635Tyrosine-protein kinase, catalytic domain
IPR023420Tyrosine-protein kinase SYK/ZAP-70, inter-SH2 domain

No MapMan annotations defined for this gene.