Gene: ENSMUSG00000026104 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000026104
Transcript Identifier
ENSMUST00000186057
Gene Type
Coding gene
Location
1 : 52122594-52159297 : positive

Family Information

Homologous gene family
HOM03P007485
(11 genes in 4 species)
specific family
Orthologous gene family
ORTHO03P018601
(5 genes in 2 species)
specific family
Duplication type
Tandem duplicate

Descriptions

gene_descr
signal transducer and activator of transcription 1

Identifiers

Type Value
UniprotA0A087WSP5
MGI103063

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001937
ISO
Genome Projectnegative regulation of endothelial cell proliferation
GO:0006351
IMP
IEA
Genome Projecttranscription, DNA-templated
GO:0006355
IEA
Genome Projectregulation of transcription, DNA-templated
GO:0007165
IEA
Genome Projectsignal transduction
GO:0007259
ISO
Genome ProjectJAK-STAT cascade
GO:0009617
IDA
Genome Projectresponse to bacterium
GO:0016525
ISO
Genome Projectnegative regulation of angiogenesis
GO:0019221
IDA
Genome Projectcytokine-mediated signaling pathway
GO:0031663
IDA
Genome Projectlipopolysaccharide-mediated signaling pathway
GO:0032496
IDA
Genome Projectresponse to lipopolysaccharide
GO:0033209
ISO
Genome Projecttumor necrosis factor-mediated signaling pathway
GO:0034240
IMP
Genome Projectnegative regulation of macrophage fusion
GO:0035458
ISO
Genome Projectcellular response to interferon-beta
GO:0043124
ISO
Genome Projectnegative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043330
IDA
Genome Projectresponse to exogenous dsRNA
GO:0045893
ISO
Genome Projectpositive regulation of transcription, DNA-templated
GO:0045944
ISO
Genome Projectpositive regulation of transcription from RNA polymerase II promoter
GO:0046725
ISO
Genome Projectnegative regulation by virus of viral protein levels in host cell
GO:0060333
ISO
Genome Projectinterferon-gamma-mediated signaling pathway
GO:0061326
ISO
Genome Projectrenal tubule development
GO:0071222
IMP
Genome Projectcellular response to lipopolysaccharide

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000978
ISO
Genome ProjectRNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000979
ISO
Genome ProjectRNA polymerase II core promoter sequence-specific DNA binding
GO:0000983
ISO
Genome Projecttranscription factor activity, RNA polymerase II core promoter sequence-specific
GO:0003677
IEA
Genome ProjectDNA binding
GO:0003690
ISO
Genome Projectdouble-stranded DNA binding
GO:0003700
IMP
IEA
Genome Projecttranscription factor activity, sequence-specific DNA binding
GO:0004871
IEA
Genome Projectsignal transducer activity
GO:0005164
ISO
Genome Projecttumor necrosis factor receptor binding
GO:0019899
ISO
Genome Projectenzyme binding
GO:0042802
ISO
Genome Projectidentical protein binding
GO:0042803
ISO
Genome Projectprotein homodimerization activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000790
ISO
Genome Projectnuclear chromatin
GO:0005634
IDA
ISO
IEA
Genome Projectnucleus
GO:0005654
ISO
Genome Projectnucleoplasm
GO:0005730
ISO
Genome Projectnucleolus
GO:0005737
IDA
ISO
IEA
Genome Projectcytoplasm
GO:0048471
ISO
Genome Projectperinuclear region of cytoplasm

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000980SH2 domain
IPR001217Transcription factor STAT
IPR008967p53-like transcription factor, DNA-binding
IPR011992EF-hand domain pair
IPR012345STAT transcription factor, DNA-binding, subdomain
IPR013799STAT transcription factor, protein interaction
IPR013800STAT transcription factor, all-alpha domain
IPR013801STAT transcription factor, DNA-binding
IPR015988STAT transcription factor, coiled coil
IPR022752Signal transducer and activation of transcription 1, TAZ2 binding domain, C-terminal

No MapMan annotations defined for this gene.