Gene: ENSMUSG00000026012 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000026012
Transcript Identifier
ENSMUST00000027165
Gene Type
Coding gene
Location
1 : 60746474-60769785 : positive

Family Information

Homologous gene family
HOM03P027517
(3 genes in 2 species)
specific family

Descriptions

gene_descr
CD28 antigen

Identifiers

Type Value
UniprotP31041
MGI88327

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0002863
IMP
Genome Projectpositive regulation of inflammatory response to antigenic stimulus
GO:0006955
IEA
Genome Projectimmune response
GO:0010628
ISO
Genome Projectpositive regulation of gene expression
GO:0010629
ISO
Genome Projectnegative regulation of gene expression
GO:0014068
IDA
Genome Projectpositive regulation of phosphatidylinositol 3-kinase signaling
GO:0031295
IDA, IMP, IGI
Genome ProjectT cell costimulation
GO:0042102
IDA, IMP
ISS, ISO
Genome Projectpositive regulation of T cell proliferation
GO:0045060
IMP
Genome Projectnegative thymic T cell selection
GO:0045066
ISO
IEA
Genome Projectregulatory T cell differentiation
GO:0045086
IMP
ISS, ISO
Genome Projectpositive regulation of interleukin-2 biosynthetic process
GO:0045840
ISS, ISO
Genome Projectpositive regulation of mitotic nuclear division
GO:0045944
IGI
Genome Projectpositive regulation of transcription from RNA polymerase II promoter
GO:0046641
IDA, IMP
Genome Projectpositive regulation of alpha-beta T cell proliferation
GO:0048304
IMP
Genome Projectpositive regulation of isotype switching to IgG isotypes
GO:0050852
IMP
Genome ProjectT cell receptor signaling pathway
GO:0051897
IDA
Genome Projectpositive regulation of protein kinase B signaling
GO:0097190
IDA
Genome Projectapoptotic signaling pathway

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0002020
ISO
IEA
Genome Projectprotease binding
GO:0005070
ISO
IEA
Genome ProjectSH3/SH2 adaptor activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001772
IDA
Genome Projectimmunological synapse
GO:0005886
ISO
IEA
Genome Projectplasma membrane
GO:0009897
IDA, IMP
ISO
IEA
Genome Projectexternal side of plasma membrane
GO:0016020
IEA
Genome Projectmembrane
GO:0016021
IEA
Genome Projectintegral component of membrane

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR003599Immunoglobulin subtype
IPR007110Immunoglobulin-like domain
IPR008093T cell antigen CD28
IPR013106Immunoglobulin V-set domain
IPR013783Immunoglobulin-like fold

No MapMan annotations defined for this gene.