Gene: ENSMUSG00000025810 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000025810
Transcript Identifier
ENSMUST00000026917
Gene Type
Coding gene
Location
8 : 128359560-128502814 : positive

Family Information

Homologous gene family
HOM03P000563
(89 genes in 8 species)
specific family
Orthologous gene family
ORTHO03P023842
(4 genes in 2 species)
specific family
Duplication type
Block duplicate

Descriptions

gene_descr
neuropilin 1

Identifiers

Type Value
UniprotP97333
MGI106206

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001525
IMP, IGI
ISO
IEA
Genome Projectangiogenesis
GO:0001569
IMP
Genome Projectpatterning of blood vessels
GO:0001764
IMP
Genome Projectneuron migration
GO:0002040
IMP
Genome Projectsprouting angiogenesis
GO:0002042
IMP
IC
Genome Projectcell migration involved in sprouting angiogenesis
GO:0007275
IEA
Genome Projectmulticellular organismal development
GO:0007399
IEA
Genome Projectnervous system development
GO:0007411
IDA, IMP
IEA
Genome Projectaxon guidance
GO:0007413
IMP
Genome Projectaxonal fasciculation
GO:0007507
IGI
Genome Projectheart development
GO:0008045
IMP
Genome Projectmotor neuron axon guidance
GO:0009887
IEA
Genome Projectorgan morphogenesis
GO:0016358
IMP
Genome Projectdendrite development
GO:0016477
IMP
Genome Projectcell migration
GO:0021612
IMP
Genome Projectfacial nerve structural organization
GO:0021636
IMP
Genome Projecttrigeminal nerve morphogenesis
GO:0021637
IMP
Genome Projecttrigeminal nerve structural organization
GO:0021649
IMP
Genome Projectvestibulocochlear nerve structural organization
GO:0021675
IMP
Genome Projectnerve development
GO:0021785
IMP
Genome Projectbranchiomotor neuron axon guidance
GO:0021828
IMP
Genome Projectgonadotrophin-releasing hormone neuronal migration to the hypothalamus
GO:0030154
IEA
Genome Projectcell differentiation
GO:0030517
IGI
Genome Projectnegative regulation of axon extension
GO:0031290
IMP
Genome Projectretinal ganglion cell axon guidance
GO:0035729
ISO
IEA
Genome Projectcellular response to hepatocyte growth factor stimulus
GO:0035767
ISO
IEA
Genome Projectendothelial cell chemotaxis
GO:0035924
IMP
Genome Projectcellular response to vascular endothelial growth factor stimulus
GO:0036486
IMP
Genome Projectventral trunk neural crest cell migration
GO:0038084
IEA
Genome Projectvascular endothelial growth factor signaling pathway
GO:0038190
IMP
Genome ProjectVEGF-activated neuropilin signaling pathway
GO:0043049
IMP
Genome Projectotic placode formation
GO:0043524
IMP
Genome Projectnegative regulation of neuron apoptotic process
GO:0048008
ISO
IEA
Genome Projectplatelet-derived growth factor receptor signaling pathway
GO:0048010
IMP
ISO
IEA
Genome Projectvascular endothelial growth factor receptor signaling pathway
GO:0048012
ISO
IEA
Genome Projecthepatocyte growth factor receptor signaling pathway
GO:0048485
IMP
Genome Projectsympathetic nervous system development
GO:0048666
IMP
Genome Projectneuron development
GO:0048841
IDA
Genome Projectregulation of axon extension involved in axon guidance
GO:0048842
IMP
Genome Projectpositive regulation of axon extension involved in axon guidance
GO:0048843
IDA
Genome Projectnegative regulation of axon extension involved in axon guidance
GO:0048844
IMP
Genome Projectartery morphogenesis
GO:0048846
IMP
Genome Projectaxon extension involved in axon guidance
GO:0050731
IMP
ISO
IEA
Genome Projectpositive regulation of peptidyl-tyrosine phosphorylation
GO:0050918
IMP
Genome Projectpositive chemotaxis
GO:0060385
IMP
Genome Projectaxonogenesis involved in innervation
GO:0060666
IMP, IGI
Genome Projectdichotomous subdivision of terminal units involved in salivary gland branching
GO:0060978
IMP
Genome Projectangiogenesis involved in coronary vascular morphogenesis
GO:0060980
IC
Genome Projectcell migration involved in coronary vasculogenesis
GO:0060982
IMP
Genome Projectcoronary artery morphogenesis
GO:0061299
IMP
Genome Projectretina vasculature morphogenesis in camera-type eye
GO:0061441
IMP
Genome Projectrenal artery morphogenesis
GO:0061549
IMP
Genome Projectsympathetic ganglion development
GO:0061551
IMP
Genome Projecttrigeminal ganglion development
GO:0061552
IMP
Genome Projectganglion morphogenesis
GO:0070374
IMP
Genome Projectpositive regulation of ERK1 and ERK2 cascade
GO:0071526
IDA, IGI
IEA
Genome Projectsemaphorin-plexin signaling pathway
GO:0071679
IMP
Genome Projectcommissural neuron axon guidance
GO:0090259
IMP
Genome Projectregulation of retinal ganglion cell axon guidance
GO:0097374
IMP
Genome Projectsensory neuron axon guidance
GO:0097490
IMP
Genome Projectsympathetic neuron projection extension
GO:0097491
IMP
Genome Projectsympathetic neuron projection guidance
GO:1901166
IMP
Genome Projectneural crest cell migration involved in autonomic nervous system development
GO:1901998
IMP
Genome Projecttoxin transport
GO:1902285
IMP
Genome Projectsemaphorin-plexin signaling pathway involved in neuron projection guidance
GO:1902287
IMP
Genome Projectsemaphorin-plexin signaling pathway involved in axon guidance
GO:1902336
IMP
Genome Projectpositive regulation of retinal ganglion cell axon guidance
GO:1902378
IMP
Genome ProjectVEGF-activated neuropilin signaling pathway involved in axon guidance
GO:1902946
IMP
Genome Projectprotein localization to early endosome
GO:1903375
IMP
Genome Projectfacioacoustic ganglion development
GO:2001237
IMP
Genome Projectnegative regulation of extrinsic apoptotic signaling pathway

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005021
IMP
IEA
Genome Projectvascular endothelial growth factor-activated receptor activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0008201
IEA
Genome Projectheparin binding
GO:0017154
IDA, IPI, IGI
IEA
Genome Projectsemaphorin receptor activity
GO:0019838
IPI
ISO
IEA
Genome Projectgrowth factor binding
GO:0038085
IPI
ISO
IEA
Genome Projectvascular endothelial growth factor binding
GO:0046872
IEA
Genome Projectmetal ion binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005615
ISO
IEA
Genome Projectextracellular space
GO:0005769
IDA
Genome Projectearly endosome
GO:0005829
ISO
IEA
Genome Projectcytosol
GO:0005883
IDA
Genome Projectneurofilament
GO:0005886
IDA
ISO
TAS, IEA
Genome Projectplasma membrane
GO:0005925
ISO
IEA
Genome Projectfocal adhesion
GO:0016020
IEA
Genome Projectmembrane
GO:0016021
IEA
Genome Projectintegral component of membrane
GO:0030424
IDA
Genome Projectaxon
GO:0097443
IDA
Genome Projectsorting endosome

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000421Coagulation factor 5/8 C-terminal domain
IPR000859CUB domain
IPR000998MAM domain
IPR008979Galactose-binding domain-like
IPR013320Concanavalin A-like lectin/glucanase domain
IPR014648Neuropilin
IPR022579Neuropilin-1, C-terminal
IPR027146Neuropilin-1

No MapMan annotations defined for this gene.