Gene: ENSMUSG00000025758 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000025758
Transcript Identifier
ENSMUST00000026858
Gene Type
Coding gene
Location
3 : 40800254-40816417 : positive

Family Information

Homologous gene family
HOM03P000001
(4368 genes in 39 species)
specific family
Orthologous gene family
ORTHO03P017787
(5 genes in 4 species)
specific family
Duplication type
Tandem duplicate   and   Block duplicate

Descriptions

gene_descr
polo-like kinase 4

Identifiers

Type Value
UniprotQ64702
MGI101783

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006468
IEA
Genome Projectprotein phosphorylation
GO:0007099
IMP
ISS, ISO
Genome Projectcentriole replication
GO:0016310
IEA
Genome Projectphosphorylation
GO:0046601
ISS, ISO
Genome Projectpositive regulation of centriole replication
GO:0060707
IMP
Genome Projecttrophoblast giant cell differentiation
GO:0098535
IMP
Genome Projectde novo centriole assembly

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000166
IEA
Genome Projectnucleotide binding
GO:0004672
IEA
Genome Projectprotein kinase activity
GO:0004674
IDA
ISO
IEA
Genome Projectprotein serine/threonine kinase activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0005524
IEA
Genome ProjectATP binding
GO:0016301
IEA
Genome Projectkinase activity
GO:0016740
IEA
Genome Projecttransferase activity
GO:0042802
IPI
Genome Projectidentical protein binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001741
IDA
Genome ProjectXY body
GO:0005634
IEA
Genome Projectnucleus
GO:0005730
IDA
IEA
Genome Projectnucleolus
GO:0005737
IEA
Genome Projectcytoplasm
GO:0005813
ISO
Genome Projectcentrosome
GO:0005814
ISS, ISO
IEA
Genome Projectcentriole
GO:0005856
IEA
Genome Projectcytoskeleton
GO:0032154
IEA
Genome Projectcleavage furrow
GO:0098536
IDA
Genome Projectdeuterosome

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000719Protein kinase domain
IPR000959POLO box duplicated domain
IPR002290Serine/threonine/dual specificity protein kinase, catalytic domain
IPR008266Tyrosine-protein kinase, active site
IPR011009Protein kinase-like domain
IPR017441Protein kinase, ATP binding site

No MapMan annotations defined for this gene.