Gene: ENSMUSG00000025747 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000025747
Transcript Identifier
ENSMUST00000026846
Gene Type
Coding gene
Location
5 : 30060996-30073547 : negative

Family Information

Homologous gene family
HOM03P001347
(53 genes in 39 species)
specific family
Orthologous gene family
ORTHO03P000949
(42 genes in 38 species)
specific family

Descriptions

gene_descr
thymidylate synthase

Identifiers

Type Value
UniprotP07607
UniprotQ544L2
MGI98878

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006206
IEA
Genome Projectpyrimidine nucleobase metabolic process
GO:0006231
IEA
Genome ProjectdTMP biosynthetic process
GO:0006235
IEA
Genome ProjectdTTP biosynthetic process
GO:0007568
IEA
Genome Projectaging
GO:0007623
IEA
Genome Projectcircadian rhythm
GO:0009165
IEA
Genome Projectnucleotide biosynthetic process
GO:0009636
IEA
Genome Projectresponse to toxic substance
GO:0014070
IEA
Genome Projectresponse to organic cyclic compound
GO:0019088
IEA
Genome Projectimmortalization of host cell by virus
GO:0019860
IEA
Genome Projecturacil metabolic process
GO:0031100
IEA
Genome Projectorgan regeneration
GO:0032259
IEA
Genome Projectmethylation
GO:0032570
IEA
Genome Projectresponse to progesterone
GO:0033189
IEA
Genome Projectresponse to vitamin A
GO:0034097
IEA
Genome Projectresponse to cytokine
GO:0042493
IEA
Genome Projectresponse to drug
GO:0045471
IEA
Genome Projectresponse to ethanol
GO:0046078
IEA
Genome ProjectdUMP metabolic process
GO:0046653
IEA
Genome Projecttetrahydrofolate metabolic process
GO:0046683
IEA
Genome Projectresponse to organophosphorus
GO:0048589
IEA
Genome Projectdevelopmental growth
GO:0051216
IEA
Genome Projectcartilage development
GO:0051384
IEA
Genome Projectresponse to glucocorticoid
GO:0051593
IEA
Genome Projectresponse to folic acid
GO:0060574
IEA
Genome Projectintestinal epithelial cell maturation

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000166
IEA
Genome Projectnucleotide binding
GO:0003729
IEA
Genome ProjectmRNA binding
GO:0004799
IEA
Genome Projectthymidylate synthase activity
GO:0005542
IEA
Genome Projectfolic acid binding
GO:0008144
IEA
Genome Projectdrug binding
GO:0008168
IEA
Genome Projectmethyltransferase activity
GO:0016740
IEA
Genome Projecttransferase activity
GO:0042803
IEA
Genome Projectprotein homodimerization activity
GO:0048037
IEA
Genome Projectcofactor binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
ISS, ISO
IEA
Genome Projectnucleus
GO:0005730
IEA
Genome Projectnucleolus
GO:0005737
ISS, ISO
IEA
Genome Projectcytoplasm
GO:0005739
ISS, ISO
IEA
Genome Projectmitochondrion
GO:0005743
ISS, ISO
IEA
Genome Projectmitochondrial inner membrane
GO:0005759
ISS, ISO
IEA
Genome Projectmitochondrial matrix
GO:0016020
IEA
Genome Projectmembrane

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000398Thymidylate synthase
IPR020940Thymidylate synthase, active site
IPR023451Thymidylate synthase/dCMP hydroxymethylase domain

No MapMan annotations defined for this gene.