Gene: ENSMUSG00000025555 (Mus musculus)

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Gene Identifier
ENSMUSG00000025555
Transcript Identifier
ENSMUST00000026635
Gene Type
Coding gene
Location
14 : 121102012-121282391 : positive

Family Information

Homologous gene family
HOM03P002207
(39 genes in 4 species)
specific family
Orthologous gene family
ORTHO03P030983
(3 genes in 2 species)
specific family
Duplication type
Block duplicate

Descriptions

gene_descr
FERM, RhoGEF (Arhgef) and pleckstrin domain protein 1 (chondrocyte-derived)

Identifiers

Type Value
UniprotF8VPU2
MGI2446173

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0007275
IEA
Genome Projectmulticellular organismal development
GO:0007416
ISS
IEA
Genome Projectsynapse assembly
GO:0010923
ISO
Genome Projectnegative regulation of phosphatase activity
GO:0035023
IEA
Genome Projectregulation of Rho protein signal transduction
GO:0043547
ISS
IEA
Genome Projectpositive regulation of GTPase activity
GO:0048813
ISS
IEA
Genome Projectdendrite morphogenesis

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005085
IEA
Genome Projectguanyl-nucleotide exchange factor activity
GO:0005089
IEA
Genome ProjectRho guanyl-nucleotide exchange factor activity
GO:0008092
IEA
Genome Projectcytoskeletal protein binding
GO:0030676
ISS
IEA
Genome ProjectRac guanyl-nucleotide exchange factor activity
GO:0048365
IEA
Genome ProjectRac GTPase binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005737
ISO
IEA
Genome Projectcytoplasm
GO:0005829
ISS
IEA
Genome Projectcytosol
GO:0005856
IEA
Genome Projectcytoskeleton
GO:0005886
IEA
Genome Projectplasma membrane
GO:0016020
IEA
Genome Projectmembrane
GO:0019898
IEA
Genome Projectextrinsic component of membrane
GO:0030054
IEA
Genome Projectcell junction
GO:0030175
IEA
Genome Projectfilopodium
GO:0030425
ISS
IEA
Genome Projectdendrite
GO:0031234
ISS
IEA
Genome Projectextrinsic component of cytoplasmic side of plasma membrane
GO:0042995
IEA
Genome Projectcell projection
GO:0043005
IEA
Genome Projectneuron projection
GO:0043197
IEA
Genome Projectdendritic spine
GO:0045202
IEA
Genome Projectsynapse

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000219Dbl homology (DH) domain
IPR000299FERM domain
IPR000798Ezrin/radixin/moesin-like
IPR001849Pleckstrin homology domain
IPR011993PH domain-like
IPR014352FERM/acyl-CoA-binding protein, 3-helical bundle
IPR014847FERM adjacent (FA)
IPR018979FERM, N-terminal
IPR018980FERM, C-terminal PH-like domain
IPR019747FERM conserved site
IPR019748FERM central domain
IPR019749Band 4.1 domain
IPR029071Ubiquitin-related domain

No MapMan annotations defined for this gene.