Gene: ENSMUSG00000025496 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000025496
Transcript Identifier
ENSMUST00000026569
Gene Type
Coding gene
Location
7 : 141292038-141294861 : positive

Family Information

Homologous gene family
HOM03P000241
(150 genes in 4 species)
specific family

Descriptions

gene_descr
dopamine receptor D4

Identifiers

Type Value
UniprotP51436
MGI94926

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000187
ISO
IEA
Genome Projectactivation of MAPK activity
GO:0001662
IEA
Genome Projectbehavioral fear response
GO:0001963
IEA
Genome Projectsynaptic transmission, dopaminergic
GO:0001975
IMP
Genome Projectresponse to amphetamine
GO:0007165
IEA
Genome Projectsignal transduction
GO:0007186
IEA
Genome ProjectG-protein coupled receptor signaling pathway
GO:0007194
ISO, IBA
IEA
Genome Projectnegative regulation of adenylate cyclase activity
GO:0007195
IMP
ISO
IEA
Genome Projectadenylate cyclase-inhibiting dopamine receptor signaling pathway
GO:0007212
ISO
IEA
Genome Projectdopamine receptor signaling pathway
GO:0007268
IBA
Genome Projectsynaptic transmission
GO:0007606
IBA
Genome Projectsensory perception of chemical stimulus
GO:0007614
IEA
Genome Projectshort-term memory
GO:0007623
IEA
Genome Projectcircadian rhythm
GO:0008306
IEA
Genome Projectassociative learning
GO:0008344
IMP
Genome Projectadult locomotory behavior
GO:0008355
IEA
Genome Projectolfactory learning
GO:0009648
IEA
Genome Projectphotoperiodism
GO:0030818
ISO
IEA
Genome Projectnegative regulation of cAMP biosynthetic process
GO:0032417
ISO
IEA
Genome Projectpositive regulation of sodium:proton antiporter activity
GO:0033674
ISO
IEA
Genome Projectpositive regulation of kinase activity
GO:0034776
ISO
IEA
Genome Projectresponse to histamine
GO:0042053
IMP
Genome Projectregulation of dopamine metabolic process
GO:0042596
IMP
Genome Projectfear response
GO:0042752
IMP
Genome Projectregulation of circadian rhythm
GO:0046928
IEA
Genome Projectregulation of neurotransmitter secretion
GO:0048148
IMP
Genome Projectbehavioral response to cocaine
GO:0048511
IEA
Genome Projectrhythmic process
GO:0048545
IEA
Genome Projectresponse to steroid hormone
GO:0050482
ISO
IEA
Genome Projectarachidonic acid secretion
GO:0050709
ISO
IEA
Genome Projectnegative regulation of protein secretion
GO:0050804
IEA
Genome Projectmodulation of synaptic transmission
GO:0050848
IEA
Genome Projectregulation of calcium-mediated signaling
GO:0060041
IEA
Genome Projectretina development in camera-type eye
GO:0060080
IMP
Genome Projectinhibitory postsynaptic potential
GO:0060406
IEA
Genome Projectpositive regulation of penile erection
GO:1901386
ISO
IEA
Genome Projectnegative regulation of voltage-gated calcium channel activity
GO:2000463
IEA
Genome Projectpositive regulation of excitatory postsynaptic potential
GO:0010579
IBA
Genome Projectpositive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001591
IMP
ISO
Genome Projectdopamine neurotransmitter receptor activity, coupled via Gi/Go
GO:0004871
IEA
Genome Projectsignal transducer activity
GO:0004930
IEA
Genome ProjectG-protein coupled receptor activity
GO:0004952
ISO
IEA
Genome Projectdopamine neurotransmitter receptor activity
GO:0008144
ISO
IEA
Genome Projectdrug binding
GO:0008227
IBA
Genome ProjectG-protein coupled amine receptor activity
GO:0017124
ISO
IEA
Genome ProjectSH3 domain binding
GO:0035240
ISO
IEA
Genome Projectdopamine binding
GO:0042802
ISO
IEA
Genome Projectidentical protein binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005737
IEA
Genome Projectcytoplasm
GO:0005886
ISO
IEA
Genome Projectplasma membrane
GO:0005887
ISO, IBA
IEA
Genome Projectintegral component of plasma membrane
GO:0005938
IEA
Genome Projectcell cortex
GO:0012506
IEA
Genome Projectvesicle membrane
GO:0016020
ISO
IEA
Genome Projectmembrane
GO:0016021
IEA
Genome Projectintegral component of membrane
GO:0030424
IEA
Genome Projectaxon
GO:0030425
IEA
Genome Projectdendrite
GO:0043025
IEA
Genome Projectneuronal cell body
GO:0043195
IEA
Genome Projectterminal bouton
GO:0043197
IEA
Genome Projectdendritic spine
GO:0043679
IEA
Genome Projectaxon terminus

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000276G protein-coupled receptor, rhodopsin-like
IPR000929Dopamine receptor family
IPR002185Dopamine D4 receptor
IPR017452GPCR, rhodopsin-like, 7TM

No MapMan annotations defined for this gene.