Gene: ENSMUSG00000025383 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000025383
Transcript Identifier
ENSMUST00000026449
Gene Type
Coding gene
Location
10 : 128296796-128297972 : negative

Family Information

Homologous gene family
HOM03P049281
(2 genes in 2 species)
specific family

Descriptions

gene_descr
interleukin 23, alpha subunit p19

Identifiers

Type Value
UniprotQ9EQ14
MGI1932410

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001916
IDA
Genome Projectpositive regulation of T cell mediated cytotoxicity
GO:0002230
IDA
ISO
Genome Projectpositive regulation of defense response to virus by host
GO:0002376
IEA
Genome Projectimmune system process
GO:0002827
IDA
ISO
Genome Projectpositive regulation of T-helper 1 type immune response
GO:0006954
IEA
Genome Projectinflammatory response
GO:0006955
IEA
Genome Projectimmune response
GO:0010535
ISO, IBA
IEA
Genome Projectpositive regulation of activation of JAK2 kinase activity
GO:0032693
ISO
IEA
Genome Projectnegative regulation of interleukin-10 production
GO:0032725
ISO
IEA
Genome Projectpositive regulation of granulocyte macrophage colony-stimulating factor production
GO:0032729
ISO
IEA
Genome Projectpositive regulation of interferon-gamma production
GO:0032733
ISO
IEA
Genome Projectpositive regulation of interleukin-10 production
GO:0032735
ISO
IEA
Genome Projectpositive regulation of interleukin-12 production
GO:0032740
ISO
IEA
Genome Projectpositive regulation of interleukin-17 production
GO:0032760
ISO
IEA
Genome Projectpositive regulation of tumor necrosis factor production
GO:0032819
ISO
IEA
Genome Projectpositive regulation of natural killer cell proliferation
GO:0042098
IDA
Genome ProjectT cell proliferation
GO:0042102
ISO, IBA
IEA
Genome Projectpositive regulation of T cell proliferation
GO:0042104
ISO
IEA
Genome Projectpositive regulation of activated T cell proliferation
GO:0042510
ISO
IEA
Genome Projectregulation of tyrosine phosphorylation of Stat1 protein
GO:0042517
ISO
IEA
Genome Projectpositive regulation of tyrosine phosphorylation of Stat3 protein
GO:0042520
ISO
IEA
Genome Projectpositive regulation of tyrosine phosphorylation of Stat4 protein
GO:0042523
ISO
IEA
Genome Projectpositive regulation of tyrosine phosphorylation of Stat5 protein
GO:0043382
IDA
Genome Projectpositive regulation of memory T cell differentiation
GO:0045087
IEA
Genome Projectinnate immune response
GO:0045672
ISO
IEA
Genome Projectpositive regulation of osteoclast differentiation
GO:0045944
IGI
Genome Projectpositive regulation of transcription from RNA polymerase II promoter
GO:0048771
IEA
Genome Projecttissue remodeling
GO:0050829
ISO
IEA
Genome Projectdefense response to Gram-negative bacterium
GO:0051135
ISO
IEA
Genome Projectpositive regulation of NK T cell activation
GO:0051142
ISO
IEA
Genome Projectpositive regulation of NK T cell proliferation
GO:0051607
IEA
Genome Projectdefense response to virus
GO:0090023
IDA
Genome Projectpositive regulation of neutrophil chemotaxis
GO:2000318
IDA
Genome Projectpositive regulation of T-helper 17 type immune response
GO:2000330
IDA
Genome Projectpositive regulation of T-helper 17 cell lineage commitment

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005125
IEA
Genome Projectcytokine activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0045519
IPI
ISO
IEA
Genome Projectinterleukin-23 receptor binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005576
IEA
Genome Projectextracellular region
GO:0005615
IDA
IEA
Genome Projectextracellular space
GO:0070743
IDA
ISO
IEA
Genome Projectinterleukin-23 complex

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR009079Four-helical cytokine-like, core
IPR010831Interleukin-23 alpha
IPR012351Four-helical cytokine, core

No MapMan annotations defined for this gene.