Gene: ENSMUSG00000025358 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000025358
Transcript Identifier
ENSMUST00000026416
Gene Type
Coding gene
Location
10 : 128699106-128704827 : negative

Family Information

Homologous gene family
HOM03P000009
(1563 genes in 39 species)
specific family
Orthologous gene family
ORTHO03P062652
(2 genes in 2 species)
specific family

Descriptions

gene_descr
cyclin-dependent kinase 2

Identifiers

Type Value
UniprotP97377
UniprotQ3UGB9
MGI104772

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000082
IDA
Genome ProjectG1/S transition of mitotic cell cycle
GO:0002088
IEA
Genome Projectlens development in camera-type eye
GO:0006281
IEA
Genome ProjectDNA repair
GO:0006468
IDA
IEA
Genome Projectprotein phosphorylation
GO:0006813
IGI
Genome Projectpotassium ion transport
GO:0006974
IEA
Genome Projectcellular response to DNA damage stimulus
GO:0007049
IEA
Genome Projectcell cycle
GO:0007067
IEA
Genome Projectmitotic nuclear division
GO:0007265
IEA
Genome ProjectRas protein signal transduction
GO:0008284
ISO
IEA
Genome Projectpositive regulation of cell proliferation
GO:0009636
IEA
Genome Projectresponse to toxic substance
GO:0016310
IEA
Genome Projectphosphorylation
GO:0016572
ISO
IEA
Genome Projecthistone phosphorylation
GO:0018105
ISO
IEA
Genome Projectpeptidyl-serine phosphorylation
GO:0031100
IEA
Genome Projectorgan regeneration
GO:0032298
IGI
Genome Projectpositive regulation of DNA-dependent DNA replication initiation
GO:0032355
IEA
Genome Projectresponse to estradiol
GO:0032869
IEA
Genome Projectcellular response to insulin stimulus
GO:0042493
IEA
Genome Projectresponse to drug
GO:0045471
IEA
Genome Projectresponse to ethanol
GO:0045893
IGI
Genome Projectpositive regulation of transcription, DNA-templated
GO:0046686
IEA
Genome Projectresponse to cadmium ion
GO:0051301
IEA
Genome Projectcell division
GO:0051321
IEA
Genome Projectmeiotic cell cycle
GO:0051591
IEA
Genome Projectresponse to cAMP
GO:0051602
IEA
Genome Projectresponse to electrical stimulus
GO:0051726
IEA
Genome Projectregulation of cell cycle
GO:0060968
ISO
IEA
Genome Projectregulation of gene silencing

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000166
IEA
Genome Projectnucleotide binding
GO:0004672
IDA
IEA
Genome Projectprotein kinase activity
GO:0004674
IEA
Genome Projectprotein serine/threonine kinase activity
GO:0004693
IDA
ISO
IEA
Genome Projectcyclin-dependent protein serine/threonine kinase activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0005524
IEA
Genome ProjectATP binding
GO:0016301
IDA
IEA
Genome Projectkinase activity
GO:0016740
IEA
Genome Projecttransferase activity
GO:0030332
ISO
IEA
Genome Projectcyclin binding
GO:0032403
IEA
Genome Projectprotein complex binding
GO:0035173
ISO
IEA
Genome Projecthistone kinase activity
GO:0046872
IEA
Genome Projectmetal ion binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000307
IPI
ISO
IEA
Genome Projectcyclin-dependent protein kinase holoenzyme complex
GO:0000781
IDA
Genome Projectchromosome, telomeric region
GO:0000793
IDA
Genome Projectcondensed chromosome
GO:0000805
IDA
Genome ProjectX chromosome
GO:0000806
IDA
Genome ProjectY chromosome
GO:0005634
IDA
ISO
IEA
Genome Projectnucleus
GO:0005654
TAS
Genome Projectnucleoplasm
GO:0005667
IDA
Genome Projecttranscription factor complex
GO:0005737
ISO
IEA
Genome Projectcytoplasm
GO:0005768
ISO
IEA
Genome Projectendosome
GO:0005815
IEA
Genome Projectmicrotubule organizing center
GO:0005829
IEA
Genome Projectcytosol
GO:0005856
IEA
Genome Projectcytoskeleton
GO:0015030
ISO
IEA
Genome ProjectCajal body
GO:0043231
IEA
Genome Projectintracellular membrane-bounded organelle

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000719Protein kinase domain
IPR002290Serine/threonine/dual specificity protein kinase, catalytic domain
IPR008271Serine/threonine-protein kinase, active site
IPR011009Protein kinase-like domain
IPR017441Protein kinase, ATP binding site

No MapMan annotations defined for this gene.