Gene: ENSMUSG00000024997 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000024997
Transcript Identifier
ENSMUST00000025961
Gene Type
Coding gene
Location
19 : 60864666-60874467 : negative

Family Information

Homologous gene family
HOM03P000356
(120 genes in 37 species)
specific family
Orthologous gene family
ORTHO03P003973
(21 genes in 15 species)
specific family

Descriptions

gene_descr
peroxiredoxin 3

Identifiers

Type Value
UniprotP20108
MGI88034

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001893
IMP
Genome Projectmaternal placenta development
GO:0006915
ISO
Genome Projectapoptotic process
GO:0006979
IMP
ISO
IEA
Genome Projectresponse to oxidative stress
GO:0007005
ISO
IEA
Genome Projectmitochondrion organization
GO:0008284
ISO
IEA
Genome Projectpositive regulation of cell proliferation
GO:0018171
ISO
IEA
Genome Projectpeptidyl-cysteine oxidation
GO:0030099
IMP
Genome Projectmyeloid cell differentiation
GO:0032496
IMP
Genome Projectresponse to lipopolysaccharide
GO:0033673
ISO
IEA
Genome Projectnegative regulation of kinase activity
GO:0034599
ISO
IEA
Genome Projectcellular response to oxidative stress
GO:0034614
ISO
IEA
Genome Projectcellular response to reactive oxygen species
GO:0042542
ISO
IEA
Genome Projectresponse to hydrogen peroxide
GO:0042744
ISO
IEA
Genome Projecthydrogen peroxide catabolic process
GO:0043066
ISO
IEA
Genome Projectnegative regulation of apoptotic process
GO:0043154
ISO
IEA
Genome Projectnegative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0051092
ISO
IEA
Genome Projectpositive regulation of NF-kappaB transcription factor activity
GO:0051881
ISO
IEA
Genome Projectregulation of mitochondrial membrane potential
GO:0055114
IEA
Genome Projectoxidation-reduction process

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004601
IEA
Genome Projectperoxidase activity
GO:0008022
ISO
IEA
Genome Projectprotein C-terminus binding
GO:0008379
ISO
IEA
Genome Projectthioredoxin peroxidase activity
GO:0016209
IEA
Genome Projectantioxidant activity
GO:0016491
IEA
Genome Projectoxidoreductase activity
GO:0019900
ISO
IEA
Genome Projectkinase binding
GO:0019901
ISO
IEA
Genome Projectprotein kinase binding
GO:0042802
IPI
Genome Projectidentical protein binding
GO:0043027
ISO
IEA
Genome Projectcysteine-type endopeptidase inhibitor activity involved in apoptotic process
GO:0051920
IEA
Genome Projectperoxiredoxin activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005737
ISO
IEA
Genome Projectcytoplasm
GO:0005739
IDA
ISO
IEA
Genome Projectmitochondrion
GO:0005769
ISO
IEA
Genome Projectearly endosome
GO:0005829
ISO
IEA
Genome Projectcytosol
GO:0008385
ISO
IEA
Genome ProjectIkappaB kinase complex
GO:0043209
IDA
Genome Projectmyelin sheath
GO:0070062
ISO
IEA
Genome Projectextracellular exosome

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000866Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant
IPR012336Thioredoxin-like fold
IPR019479Peroxiredoxin, C-terminal

No MapMan annotations defined for this gene.