Gene: ENSMUSG00000024986 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000024986
Transcript Identifier
ENSMUST00000025944
Gene Type
Coding gene
Location
19 : 37434870-37439805 : positive

Family Information

Homologous gene family
HOM03P000104
(258 genes in 4 species)
specific family
Orthologous gene family
ORTHO03P063898
(2 genes in 2 species)
specific family
Duplication type
Block duplicate

Descriptions

gene_descr
hematopoietically expressed homeobox

Identifiers

Type Value
UniprotP43120
MGI96086

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000122
IDA
ISO
IEA
Genome Projectnegative regulation of transcription from RNA polymerase II promoter
GO:0001570
IMP
Genome Projectvasculogenesis
GO:0001701
IMP
Genome Projectin utero embryonic development
GO:0001889
IMP
Genome Projectliver development
GO:0002009
IMP
Genome Projectmorphogenesis of an epithelium
GO:0002573
IMP
Genome Projectmyeloid leukocyte differentiation
GO:0006351
IEA
Genome Projecttranscription, DNA-templated
GO:0006355
IEA
Genome Projectregulation of transcription, DNA-templated
GO:0006357
IMP
Genome Projectregulation of transcription from RNA polymerase II promoter
GO:0006406
ISO
IEA
Genome ProjectmRNA export from nucleus
GO:0007165
IMP
Genome Projectsignal transduction
GO:0007219
IDA
Genome ProjectNotch signaling pathway
GO:0007275
IEA
Genome Projectmulticellular organismal development
GO:0007492
IMP
Genome Projectendoderm development
GO:0008283
ISO
IEA
Genome Projectcell proliferation
GO:0009611
IEA
Genome Projectresponse to wounding
GO:0009887
IMP
Genome Projectorgan morphogenesis
GO:0009952
IMP
Genome Projectanterior/posterior pattern specification
GO:0016055
IEA
Genome ProjectWnt signaling pathway
GO:0016525
IDA
IEA
Genome Projectnegative regulation of angiogenesis
GO:0016973
ISO
IEA
Genome Projectpoly(A)+ mRNA export from nucleus
GO:0022027
IMP
Genome Projectinterkinetic nuclear migration
GO:0030097
IMP
Genome Projecthemopoiesis
GO:0030154
IEA
Genome Projectcell differentiation
GO:0030177
IMP
Genome Projectpositive regulation of Wnt signaling pathway
GO:0030183
IMP
Genome ProjectB cell differentiation
GO:0030878
IMP
Genome Projectthyroid gland development
GO:0030900
IMP
Genome Projectforebrain development
GO:0030948
IDA
IEA
Genome Projectnegative regulation of vascular endothelial growth factor receptor signaling pathway
GO:0031016
IMP
Genome Projectpancreas development
GO:0034504
ISO
IEA
Genome Projectprotein localization to nucleus
GO:0035050
IMP
Genome Projectembryonic heart tube development
GO:0035264
IMP
Genome Projectmulticellular organism growth
GO:0042127
IMP
Genome Projectregulation of cell proliferation
GO:0043434
IEA
Genome Projectresponse to peptide hormone
GO:0045736
ISO
IEA
Genome Projectnegative regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0045892
IDA
ISO
IEA
Genome Projectnegative regulation of transcription, DNA-templated
GO:0045944
ISO
IEA
Genome Projectpositive regulation of transcription from RNA polymerase II promoter
GO:0048568
IMP
Genome Projectembryonic organ development
GO:0048729
IMP
Genome Projecttissue morphogenesis
GO:0048853
IMP
Genome Projectforebrain morphogenesis
GO:0060431
IMP
Genome Projectprimary lung bud formation
GO:0061009
IMP
Genome Projectcommon bile duct development
GO:0061010
IMP
Genome Projectgall bladder development
GO:0061011
IMP
Genome Projecthepatic duct development
GO:0061017
IMP
Genome Projecthepatoblast differentiation
GO:0070365
IMP
Genome Projecthepatocyte differentiation
GO:0071103
ISO
IEA
Genome ProjectDNA conformation change
GO:0090009
IMP, IGI
Genome Projectprimitive streak formation

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000977
IDA
Genome ProjectRNA polymerase II regulatory region sequence-specific DNA binding
GO:0000978
ISO
IEA
Genome ProjectRNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001078
ISO
IEA
Genome Projecttranscriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0001227
IDA
Genome Projecttranscriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
GO:0003677
IEA
Genome ProjectDNA binding
GO:0003682
IDA
Genome Projectchromatin binding
GO:0003700
IDA
Genome Projecttranscription factor activity, sequence-specific DNA binding
GO:0008134
ISO
IEA
Genome Projecttranscription factor binding
GO:0008190
ISO
IEA
Genome Projecteukaryotic initiation factor 4E binding
GO:0008301
ISO
IEA
Genome ProjectDNA binding, bending
GO:0042803
ISO
IEA
Genome Projectprotein homodimerization activity
GO:0043565
ISS, ISO
IEA
Genome Projectsequence-specific DNA binding
GO:0044212
ISO
IEA
Genome Projecttranscription regulatory region DNA binding
GO:0070491
ISO
IEA
Genome Projectrepressing transcription factor binding
GO:0071837
IPI
Genome ProjectHMG box domain binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IDA
ISO
IEA
Genome Projectnucleus
GO:0005737
IDA
ISO
IEA
Genome Projectcytoplasm
GO:0032993
ISO
IEA
Genome Projectprotein-DNA complex

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR001356Homeobox domain
IPR009057Homeodomain-like
IPR017970Homeobox, conserved site
IPR020479Homeodomain, metazoa

No MapMan annotations defined for this gene.