Gene: ENSMUSG00000024959 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000024959
Transcript Identifier
ENSMUST00000025910
Gene Type
Coding gene
Location
19 : 6942323-6951524 : positive

Family Information

Homologous gene family
HOM03P052641
(orphan gene)
specific family

Descriptions

gene_descr
BCL2-associated agonist of cell death

Identifiers

Type Value
UniprotQ61337
MGI1096330

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001666
IEA
Genome Projectresponse to hypoxia
GO:0001836
IMP
Genome Projectrelease of cytochrome c from mitochondria
GO:0006007
IMP
Genome Projectglucose catabolic process
GO:0006915
ISO
IEA
Genome Projectapoptotic process
GO:0006919
IDA
Genome Projectactivation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0008283
IDA
Genome Projectcell proliferation
GO:0008625
IMP
Genome Projectextrinsic apoptotic signaling pathway via death domain receptors
GO:0008630
IDA, IMP
Genome Projectintrinsic apoptotic signaling pathway in response to DNA damage
GO:0009725
IEA
Genome Projectresponse to hormone
GO:0009749
IEA
Genome Projectresponse to glucose
GO:0010033
IEA
Genome Projectresponse to organic substance
GO:0010918
IMP
Genome Projectpositive regulation of mitochondrial membrane potential
GO:0014070
IEA
Genome Projectresponse to organic cyclic compound
GO:0019050
IDA, IMP
Genome Projectsuppression by virus of host apoptotic process
GO:0019221
IDA
Genome Projectcytokine-mediated signaling pathway
GO:0032024
IMP
Genome Projectpositive regulation of insulin secretion
GO:0032355
IEA
Genome Projectresponse to estradiol
GO:0032570
IEA
Genome Projectresponse to progesterone
GO:0033133
IMP
Genome Projectpositive regulation of glucokinase activity
GO:0033574
IEA
Genome Projectresponse to testosterone
GO:0034201
IEA
Genome Projectresponse to oleic acid
GO:0035774
IMP
Genome Projectpositive regulation of insulin secretion involved in cellular response to glucose stimulus
GO:0042493
IEA
Genome Projectresponse to drug
GO:0042542
IEA
Genome Projectresponse to hydrogen peroxide
GO:0042593
IMP
Genome Projectglucose homeostasis
GO:0042981
IDA
Genome Projectregulation of apoptotic process
GO:0043065
IDA
ISO
IEA
Genome Projectpositive regulation of apoptotic process
GO:0043200
IEA
Genome Projectresponse to amino acid
GO:0043280
ISS, ISO
IEA
Genome Projectpositive regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043281
IMP
Genome Projectregulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0044342
IMP
Genome Projecttype B pancreatic cell proliferation
GO:0045471
IEA
Genome Projectresponse to ethanol
GO:0045579
IMP
Genome Projectpositive regulation of B cell differentiation
GO:0045582
IMP
Genome Projectpositive regulation of T cell differentiation
GO:0045862
ISO
IEA
Genome Projectpositive regulation of proteolysis
GO:0045918
ISO
IEA
Genome Projectnegative regulation of cytolysis
GO:0046031
IMP
Genome ProjectADP metabolic process
GO:0046034
IMP
Genome ProjectATP metabolic process
GO:0046902
ISS, ISO
IEA
Genome Projectregulation of mitochondrial membrane permeability
GO:0046931
ISS, ISO
IEA
Genome Projectpore complex assembly
GO:0050679
ISS, ISO
IEA
Genome Projectpositive regulation of epithelial cell proliferation
GO:0051384
IEA
Genome Projectresponse to glucocorticoid
GO:0051592
IEA
Genome Projectresponse to calcium ion
GO:0060139
IDA
Genome Projectpositive regulation of apoptotic process by virus
GO:0060154
IDA
Genome Projectcellular process regulating host cell cycle in response to virus
GO:0071247
IEA
Genome Projectcellular response to chromate
GO:0071260
IEA
Genome Projectcellular response to mechanical stimulus
GO:0071310
ISO
Genome Projectcellular response to organic substance
GO:0071316
ISS, ISO
IEA
Genome Projectcellular response to nicotine
GO:0071396
IEP
Genome Projectcellular response to lipid
GO:0071456
IEA
Genome Projectcellular response to hypoxia
GO:0090200
ISO
IEA
Genome Projectpositive regulation of release of cytochrome c from mitochondria
GO:0097190
IDA, IMP
Genome Projectapoptotic signaling pathway
GO:0097191
ISO
IEA
Genome Projectextrinsic apoptotic signaling pathway
GO:0097192
IDA, IMP, IGI
Genome Projectextrinsic apoptotic signaling pathway in absence of ligand
GO:0097193
ISS, ISO
IEA
Genome Projectintrinsic apoptotic signaling pathway
GO:0097202
ISO
IEA
Genome Projectactivation of cysteine-type endopeptidase activity
GO:1901216
IEA
Genome Projectpositive regulation of neuron death
GO:2000078
IMP
Genome Projectpositive regulation of type B pancreatic cell development

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005515
IPI
Genome Projectprotein binding
GO:0005543
ISS, ISO
IEA
Genome Projectphospholipid binding
GO:0008289
ISS, ISO
IEA
Genome Projectlipid binding
GO:0008656
IDA
ISO
IEA
Genome Projectcysteine-type endopeptidase activator activity involved in apoptotic process
GO:0019901
ISO
IEA
Genome Projectprotein kinase binding
GO:0019903
IPI
Genome Projectprotein phosphatase binding
GO:0030346
IEA
Genome Projectprotein phosphatase 2B binding
GO:0043422
IEA
Genome Projectprotein kinase B binding
GO:0046982
IPI
Genome Projectprotein heterodimerization activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005737
IDA
IEA
Genome Projectcytoplasm
GO:0005739
IDA
ISO
IEA
Genome Projectmitochondrion
GO:0005741
ISS, ISO
IEA
Genome Projectmitochondrial outer membrane
GO:0005829
IDA
ISO
TAS, IEA
Genome Projectcytosol
GO:0016020
IEA
Genome Projectmembrane

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR018868Bcl2-associated agonist of cell death

No MapMan annotations defined for this gene.