Gene: ENSMUSG00000024927 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000024927
Transcript Identifier
ENSMUST00000025867
Gene Type
Coding gene
Location
19 : 5637835-5647416 : positive

Family Information

Homologous gene family
HOM03P008110
(10 genes in 3 species)
specific family
Orthologous gene family
ORTHO03P075128
(2 genes in 2 species)
specific family

Descriptions

gene_descr
v-rel reticuloendotheliosis viral oncogene homolog A (avian)

Identifiers

Type Value
UniprotQ04207
UniprotQ548Y4
MGI103290

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000122
ISO, IBA
IEA
Genome Projectnegative regulation of transcription from RNA polymerase II promoter
GO:0001889
IMP
Genome Projectliver development
GO:0001942
IMP
Genome Projecthair follicle development
GO:0006117
IEA
Genome Projectacetaldehyde metabolic process
GO:0006351
IEA
Genome Projecttranscription, DNA-templated
GO:0006355
IEA
Genome Projectregulation of transcription, DNA-templated
GO:0006366
ISO
Genome Projecttranscription from RNA polymerase II promoter
GO:0006952
IMP
Genome Projectdefense response
GO:0006954
ISO, IBA
IEA
Genome Projectinflammatory response
GO:0007249
IBA
Genome ProjectI-kappaB kinase/NF-kappaB signaling
GO:0007568
IEA
Genome Projectaging
GO:0008284
ISS, ISO
IEA
Genome Projectpositive regulation of cell proliferation
GO:0009612
IEA
Genome Projectresponse to mechanical stimulus
GO:0009617
IDA
Genome Projectresponse to bacterium
GO:0009887
IMP
Genome Projectorgan morphogenesis
GO:0010033
ISO
IEA
Genome Projectresponse to organic substance
GO:0010035
IEA
Genome Projectresponse to inorganic substance
GO:0010224
ISO
IEA
Genome Projectresponse to UV-B
GO:0014040
IEA
Genome Projectpositive regulation of Schwann cell differentiation
GO:0014070
IEA
Genome Projectresponse to organic cyclic compound
GO:0019221
ISO
IEA
Genome Projectcytokine-mediated signaling pathway
GO:0032332
IEA
Genome Projectpositive regulation of chondrocyte differentiation
GO:0032495
IDA
Genome Projectresponse to muramyl dipeptide
GO:0032496
IEA
Genome Projectresponse to lipopolysaccharide
GO:0032570
IEA
Genome Projectresponse to progesterone
GO:0032868
IEA
Genome Projectresponse to insulin
GO:0033590
IEA
Genome Projectresponse to cobalamin
GO:0034097
IBA
IEA
Genome Projectresponse to cytokine
GO:0035994
IDA
Genome Projectresponse to muscle stretch
GO:0038061
IBA
Genome ProjectNIK/NF-kappaB signaling
GO:0042177
IMP
Genome Projectnegative regulation of protein catabolic process
GO:0042493
IEA
Genome Projectresponse to drug
GO:0042542
IEA
Genome Projectresponse to hydrogen peroxide
GO:0043066
IDA
ISO
IEA
Genome Projectnegative regulation of apoptotic process
GO:0043123
IDA
IEA
Genome Projectpositive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043200
IEA
Genome Projectresponse to amino acid
GO:0043278
IEA
Genome Projectresponse to morphine
GO:0045084
IDA
Genome Projectpositive regulation of interleukin-12 biosynthetic process
GO:0045087
IBA
Genome Projectinnate immune response
GO:0045892
ISO
IEA
Genome Projectnegative regulation of transcription, DNA-templated
GO:0045893
IDA, IMP
ISO
TAS, IEA
Genome Projectpositive regulation of transcription, DNA-templated
GO:0045944
ISS, ISO, IBA
IEA
Genome Projectpositive regulation of transcription from RNA polymerase II promoter
GO:0046627
IEA
Genome Projectnegative regulation of insulin receptor signaling pathway
GO:0050727
IDA
Genome Projectregulation of inflammatory response
GO:0051092
IDA
ISO
IEA
Genome Projectpositive regulation of NF-kappaB transcription factor activity
GO:0051591
IEA
Genome Projectresponse to cAMP
GO:0070301
ISS, ISO
IEA
Genome Projectcellular response to hydrogen peroxide
GO:0070431
ISO
IEA
Genome Projectnucleotide-binding oligomerization domain containing 2 signaling pathway
GO:0070555
ISO
IEA
Genome Projectresponse to interleukin-1
GO:0071222
IEP
IEA
Genome Projectcellular response to lipopolysaccharide
GO:0071316
ISO
IEA
Genome Projectcellular response to nicotine
GO:0071347
ISO
IEA
Genome Projectcellular response to interleukin-1
GO:0071354
ISO
IEA
Genome Projectcellular response to interleukin-6
GO:0071356
ISS, ISO
IEA
Genome Projectcellular response to tumor necrosis factor
GO:0071375
ISO
IEA
Genome Projectcellular response to peptide hormone stimulus
GO:1901223
ISO
Genome Projectnegative regulation of NIK/NF-kappaB signaling
GO:2000630
ISO
IEA
Genome Projectpositive regulation of miRNA metabolic process
GO:2001237
IDA
ISO
IEA
Genome Projectnegative regulation of extrinsic apoptotic signaling pathway

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000977
IDA
ISO
IEA
Genome ProjectRNA polymerase II regulatory region sequence-specific DNA binding
GO:0000978
ISO
IEA
Genome ProjectRNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000980
ISO
IEA
Genome ProjectRNA polymerase II distal enhancer sequence-specific DNA binding
GO:0001077
ISO
IEA
Genome Projecttranscriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0001078
ISO
IEA
Genome Projecttranscriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0001205
ISO
IEA
Genome Projecttranscriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding
GO:0003677
IDA
ISO
IEA
Genome ProjectDNA binding
GO:0003682
IDA
ISO
IEA
Genome Projectchromatin binding
GO:0003700
IDA
ISO
IEA
Genome Projecttranscription factor activity, sequence-specific DNA binding
GO:0003705
IDA
ISO
IEA
Genome Projecttranscription factor activity, RNA polymerase II distal enhancer sequence-specific binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0008134
ISO
IEA
Genome Projecttranscription factor binding
GO:0019899
IPI
Genome Projectenzyme binding
GO:0019901
IPI
ISO
IEA
Genome Projectprotein kinase binding
GO:0031490
ISO
Genome Projectchromatin DNA binding
GO:0031625
ISO
IEA
Genome Projectubiquitin protein ligase binding
GO:0032403
IEA
Genome Projectprotein complex binding
GO:0033613
ISO
IEA
Genome Projectactivating transcription factor binding
GO:0042301
ISO
IEA
Genome Projectphosphate ion binding
GO:0042802
ISO
IEA
Genome Projectidentical protein binding
GO:0042803
ISO
Genome Projectprotein homodimerization activity
GO:0042805
IPI
ISO
Genome Projectactinin binding
GO:0042826
ISO
IEA
Genome Projecthistone deacetylase binding
GO:0043565
IDA
IEA
Genome Projectsequence-specific DNA binding
GO:0044212
ISO
IEA
Genome Projecttranscription regulatory region DNA binding
GO:0046982
ISO
IEA
Genome Projectprotein heterodimerization activity
GO:0047485
ISO
IEA
Genome Projectprotein N-terminus binding
GO:0051059
ISO
IEA
Genome ProjectNF-kappaB binding
GO:0070491
ISO
IEA
Genome Projectrepressing transcription factor binding
GO:0071532
IPI
Genome Projectankyrin repeat binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IDA
ISO
IEA
Genome Projectnucleus
GO:0005654
IBA
Genome Projectnucleoplasm
GO:0005667
ISO
IEA
Genome Projecttranscription factor complex
GO:0005737
IDA
ISO
IEA
Genome Projectcytoplasm
GO:0005829
IDA
ISO
IEA
Genome Projectcytosol
GO:0033256
IBA
Genome ProjectI-kappaB/NF-kappaB complex
GO:0043234
IEA
Genome Projectprotein complex
GO:0071159
TAS, IEA
Genome ProjectNF-kappaB complex

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000451NF-kappa-B/Dorsal
IPR002909IPT domain
IPR008967p53-like transcription factor, DNA-binding
IPR011539Rel homology domain (RHD), DNA-binding domain
IPR013783Immunoglobulin-like fold
IPR014756Immunoglobulin E-set
IPR030492Rel homology domain, conserved site
IPR032397Rel homology dimerisation domain

No MapMan annotations defined for this gene.