Gene: ENSMUSG00000024913 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000024913
Transcript Identifier
ENSMUST00000025856
Gene Type
Coding gene
Location
19 : 3585030-3686442 : negative

Family Information

Homologous gene family
HOM03P001101
(58 genes in 4 species)
specific family
Orthologous gene family
ORTHO03P005166
(16 genes in 4 species)
specific family

Descriptions

gene_descr
low density lipoprotein receptor-related protein 5

Identifiers

Type Value
UniprotQ91VN0
MGI1278315

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001702
IGI
Genome Projectgastrulation with mouth forming second
GO:0001944
IMP
Genome Projectvasculature development
GO:0002053
ISO
IEA
Genome Projectpositive regulation of mesenchymal cell proliferation
GO:0002076
IMP
Genome Projectosteoblast development
GO:0006007
ISO
IEA
Genome Projectglucose catabolic process
GO:0006897
IEA
Genome Projectendocytosis
GO:0007275
IEA
Genome Projectmulticellular organismal development
GO:0008203
IMP
Genome Projectcholesterol metabolic process
GO:0008217
ISO
IEA
Genome Projectregulation of blood pressure
GO:0008284
ISO
IEA
Genome Projectpositive regulation of cell proliferation
GO:0009952
IGI
Genome Projectanterior/posterior pattern specification
GO:0016055
IDA, IGI
ISO
IEA
Genome ProjectWnt signaling pathway
GO:0033690
IMP
Genome Projectpositive regulation of osteoblast proliferation
GO:0035019
IMP
Genome Projectsomatic stem cell population maintenance
GO:0035108
IGI
Genome Projectlimb morphogenesis
GO:0035426
IDA
Genome Projectextracellular matrix-cell signaling
GO:0042074
IGI
Genome Projectcell migration involved in gastrulation
GO:0042632
ISO, IBA
IEA
Genome Projectcholesterol homeostasis
GO:0042733
IGI
Genome Projectembryonic digit morphogenesis
GO:0042981
IMP
Genome Projectregulation of apoptotic process
GO:0044332
ISO, IBA
IEA
Genome ProjectWnt signaling pathway involved in dorsal/ventral axis specification
GO:0045600
ISO
IEA
Genome Projectpositive regulation of fat cell differentiation
GO:0045668
ISO
IEA
Genome Projectnegative regulation of osteoblast differentiation
GO:0045840
ISO
IEA
Genome Projectpositive regulation of mitotic nuclear division
GO:0045893
IDA
ISO
IEA
Genome Projectpositive regulation of transcription, DNA-templated
GO:0045944
ISO
IEA
Genome Projectpositive regulation of transcription from RNA polymerase II promoter
GO:0046849
IMP, IGI
Genome Projectbone remodeling
GO:0046850
IMP
Genome Projectregulation of bone remodeling
GO:0048539
ISO, IBA
IEA
Genome Projectbone marrow development
GO:0051091
IDA
Genome Projectpositive regulation of sequence-specific DNA binding transcription factor activity
GO:0060033
IMP
Genome Projectanatomical structure regression
GO:0060042
ISO
IEA
Genome Projectretina morphogenesis in camera-type eye
GO:0060070
IDA, IMP
ISO
IEA
Genome Projectcanonical Wnt signaling pathway
GO:0060348
IMP
Genome Projectbone development
GO:0060349
ISO
IEA
Genome Projectbone morphogenesis
GO:0060444
IMP
Genome Projectbranching involved in mammary gland duct morphogenesis
GO:0060603
IGI
Genome Projectmammary gland duct morphogenesis
GO:0060612
ISO, IBA
IEA
Genome Projectadipose tissue development
GO:0060764
IMP
Genome Projectcell-cell signaling involved in mammary gland development
GO:0060828
ISO
IEA
Genome Projectregulation of canonical Wnt signaling pathway
GO:0061178
IMP
Genome Projectregulation of insulin secretion involved in cellular response to glucose stimulus
GO:0061299
IMP, IGI
Genome Projectretina vasculature morphogenesis in camera-type eye
GO:0061304
ISO, IBA
IEA
Genome Projectretinal blood vessel morphogenesis
GO:0071901
ISO
IEA
Genome Projectnegative regulation of protein serine/threonine kinase activity
GO:1902262
IMP
Genome Projectapoptotic process involved in patterning of blood vessels

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005515
IPI
Genome Projectprotein binding
GO:0017147
IPI
Genome ProjectWnt-protein binding
GO:0042813
IDA
Genome ProjectWnt-activated receptor activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005739
IDA
Genome Projectmitochondrion
GO:0005783
IEA
Genome Projectendoplasmic reticulum
GO:0005886
ISO, IBA
IEA
Genome Projectplasma membrane
GO:0016020
IEA
Genome Projectmembrane
GO:0016021
IEA
Genome Projectintegral component of membrane
GO:0043235
ISO, IBA
IEA
Genome Projectreceptor complex

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000033LDLR class B repeat
IPR000742EGF-like domain
IPR002172Low-density lipoprotein (LDL) receptor class A repeat
IPR011042Six-bladed beta-propeller, TolB-like
IPR017049Low density lipoprotein receptor-related protein 5/6
IPR023415Low-density lipoprotein (LDL) receptor class A, conserved site

No MapMan annotations defined for this gene.