Gene: ENSMUSG00000024778 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000024778
Transcript Identifier
ENSMUST00000025691
Gene Type
Coding gene
Location
19 : 34290715-34327324 : positive

Family Information

Homologous gene family
HOM03P025700
(3 genes in 2 species)
specific family

Descriptions

gene_descr
Fas (TNF receptor superfamily member 6)

Identifiers

Type Value
UniprotP25446
MGI95484

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0002377
IMP
Genome Projectimmunoglobulin production
GO:0003014
IMP
Genome Projectrenal system process
GO:0006915
IMP
ISO
IEA
Genome Projectapoptotic process
GO:0006924
IDA, IMP
Genome Projectactivation-induced cell death of T cells
GO:0006925
IDA, IMP
Genome Projectinflammatory cell apoptotic process
GO:0006927
IDA
Genome Projecttransformed cell apoptotic process
GO:0006955
IEA
Genome Projectimmune response
GO:0007165
IEA
Genome Projectsignal transduction
GO:0007623
IEP
Genome Projectcircadian rhythm
GO:0008625
IDA, IMP, IGI
Genome Projectextrinsic apoptotic signaling pathway via death domain receptors
GO:0009636
IMP
Genome Projectresponse to toxic substance
GO:0010467
IMP
Genome Projectgene expression
GO:0019724
IMP
Genome ProjectB cell mediated immunity
GO:0032464
IDA
Genome Projectpositive regulation of protein homooligomerization
GO:0043029
IMP
Genome ProjectT cell homeostasis
GO:0043065
ISO
IEA
Genome Projectpositive regulation of apoptotic process
GO:0043066
IDA
Genome Projectnegative regulation of apoptotic process
GO:0045060
IMP
Genome Projectnegative thymic T cell selection
GO:0045619
IMP
Genome Projectregulation of lymphocyte differentiation
GO:0045637
IMP
Genome Projectregulation of myeloid cell differentiation
GO:0048536
IMP
Genome Projectspleen development
GO:0050869
IMP
Genome Projectnegative regulation of B cell activation
GO:0051260
IDA
Genome Projectprotein homooligomerization
GO:0051384
IMP
Genome Projectresponse to glucocorticoid
GO:0051402
IMP
Genome Projectneuron apoptotic process
GO:0071260
IEA
Genome Projectcellular response to mechanical stimulus
GO:0071285
IMP
Genome Projectcellular response to lithium ion
GO:0071455
ISO
IEA
Genome Projectcellular response to hyperoxia
GO:0090200
IC
Genome Projectpositive regulation of release of cytochrome c from mitochondria
GO:0097049
IMP
Genome Projectmotor neuron apoptotic process
GO:0097190
IDA
Genome Projectapoptotic signaling pathway
GO:0097191
IDA, IMP
ISO
IEA
Genome Projectextrinsic apoptotic signaling pathway
GO:0097192
IMP
Genome Projectextrinsic apoptotic signaling pathway in absence of ligand
GO:0097284
IGI
Genome Projecthepatocyte apoptotic process
GO:0097527
IGI
ISO
IEA
Genome Projectnecroptotic signaling pathway
GO:2001241
IMP
Genome Projectpositive regulation of extrinsic apoptotic signaling pathway in absence of ligand

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004888
IEA
Genome Projecttransmembrane signaling receptor activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0019900
ISO
IEA
Genome Projectkinase binding
GO:0042802
ISO
IEA
Genome Projectidentical protein binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005576
IDA
Genome Projectextracellular region
GO:0005634
ISO
IEA
Genome Projectnucleus
GO:0005737
ISO
IEA
Genome Projectcytoplasm
GO:0005886
ISO
IEA
Genome Projectplasma membrane
GO:0009897
IDA
Genome Projectexternal side of plasma membrane
GO:0009986
IDA
ISO
IEA
Genome Projectcell surface
GO:0016020
IEA
Genome Projectmembrane
GO:0016021
IEA
Genome Projectintegral component of membrane
GO:0031264
ISO
IEA
Genome Projectdeath-inducing signaling complex
GO:0031265
IDA
ISO
IEA
Genome ProjectCD95 death-inducing signaling complex
GO:0045121
ISO
IEA
Genome Projectmembrane raft
GO:0070062
ISO
IEA
Genome Projectextracellular exosome

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000488Death domain
IPR001368TNFR/NGFR cysteine-rich region
IPR008063Fas receptor
IPR011029Death-like domain

No MapMan annotations defined for this gene.